A LATITUDINAL CLINE IN A DROSOPHILA CLOCK GENE
A LATITUDINAL CLINE IN A DROSOPHILA CLOCK GENE
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DOI：
10.1098/rspb.1992.0128
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发表时间：
1992-10-22
影响因子：
4.7
通讯作者：
KYRIACOU, CP
中科院分区：
文献类型：
--
作者：
COSTA, R;PEIXOTO, AA;KYRIACOU, CP
时钟基因周期决定了果蝇的生物节律性，并编码一种蛋白质，其特征是一系列交替的苏氨酸-甘氨酸对。编码苏氨酸-甘氨酸重复序列的小卫星区域在自然果蝇种群中的长度是多态的。在本文中，我们报告了这种多态性在欧洲和北非的地理分析。沿沿着南北轴观察到一个强倾斜模式。我们建议的可能性，长度多态性可以保持热选择，因为苏氨酸-甘氨酸区域已被证明提供昼夜节律表型的热稳定性。
The clock gene period determines biological rhythmicity in Drosophila melanogaster and encodes a protein characterized by an alternating series of threonine-glycine pairs. The minisatellite region encoding the threonine-glycine repeat is polymorphic in length in natural Drosophila melanogaster populations. In this paper we report the geographical analysis of this polymorphism within Europe and North Africa. A robust clinal pattern is observed along a north-south axis. We suggest the possibility that the length polymorphism could be maintained by thermal selection because the threonine-glycine region has been shown to provide thermostability to the circadian phenotype.