Comparison of maximum cross-correlation coefficient between blood pressure and heart rate with traditional index associated with baroreflex sensitivity

Comparison of maximum cross-correlation coefficient between blood pressure and heart rate with traditional index associated with baroreflex sensitivity
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血压、心率最大互相关系数与压力反射敏感度相关传统指标的比较

DOI:
10.1109/iembs.2008.4649726
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发表时间:
2008
期刊:
2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
影响因子:
--
通讯作者:
S. Nitta
S. Nitta
中科院分区:
--
文献类型:
--
作者:
N. Sugita;M. Yoshizawa;M. Abe;A. Tanaka;S. Chiba;T. Yambe;S. Nitta

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一般来说,很难根据单一生理参数(如心率变异性)比较受试者对某种刺激的生物反应,因为其值存在很大的个体差异。这个问题的解决方案是利用生理参数之间的相关性。在以往的研究中,当受试者受到视觉刺激的强烈影响时,心率和血压变异性之间的最大互相关系数发生变化。在目前的工作中,该指数与传统的动脉压力反射增益相关的指数进行了比较,以探讨该指数变化的机制。对28名健康成人的静息心率和连续血压进行了5分钟的测量和分析。结果表明,这两个指标的变化趋势相似,但它们之间的平均值几乎没有相关性。此外,从血压变异性到心率变异性的滞后时间与传统指标呈负相关。
In general, it is difficult to compare biological reactions to some kind of stimulation among subjects on the basis of a single physiological parameter such as heart rate variability because there is a large individual variability in its values. A solution to this problem is to utilize the correlation between physiological parameters. In previous works, the maximum cross-correlation coefficient between heart rate and blood pressure variabilities changed when subjects were strongly affected by visual stimulation. In the present work, this index was compared with a traditional one associated with the arterial baroreflex gain to investigate the mechanism of the change in the index. Resting heart rate and continuous blood pressure of twenty-eight healthy adults were measured for five minutes and analyzed. The results showed that these two indices changed similarly to each other while there was little correlation in the mean value between them. Furthermore, the lag time from blood pressure variability to heart rate variability was inversely correlated with the traditional index.