A STUDY OF SERUM PROLACTIN LEVELS IN SCHIZOPHRENIA - COMPARISON OF MALES AND FEMALES
A STUDY OF SERUM PROLACTIN LEVELS IN SCHIZOPHRENIA - COMPARISON OF MALES AND FEMALES
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DOI：
10.1111/j.1440-1681.1992.tb00511.x
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发表时间：
1992-09-01
影响因子：
2.9
通讯作者：
KANAGASABAPATHY, AS
中科院分区：
文献类型：
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作者：
KURUVILLA, A;PEEDICAYIL, J;KANAGASABAPATHY, AS
1. 在大量精神分裂症患者（67 名男性和 42 名女性）和正常受试者（78 名男性和 42 名女性）中测量了血清催乳素水平。2．除15-29岁年龄组外，患者和对照组的血清催乳素水平没有显着差异。无论是患者还是对照组，男女血清催乳素水平均无显着差异。 3．开始服用抗精神病药物后，女性患者血清催乳素水平的上升幅度高于男性，尽管女性患者接受的抗精神病药物剂量较低。4．这些数据表明，未接受药物治疗的男性和女性的血清催乳素水平相似；然而，女性催乳素对抗精神病药物的反应比男性更大。
1. Serum prolactin levels were measured in large cohorts of schizophrenic patients (67 males and 42 females) and normal subjects (78 males and 42 females).2. There was no significant differences between the serum prolactin levels of patients and controls, except in the age group 15-29 years. There were no significant differences between the serum prolactin levels of males and females, either among the patients or the control subjects.3. The rise in serum prolactin levels after the commencement of neuroleptic medication in the patients was greater in females than in males even though the female patients received neuroleptics at lower doses.4. These data indicate that serum prolactin levels in unmedicated males and females are similar; however, the prolactin response to neuroleptic medication is greater in females than in males.