THE DEXAMETHASONE SUPPRESSION TEST FOR MELANCHOLIA
THE DEXAMETHASONE SUPPRESSION TEST FOR MELANCHOLIA
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DOI：
10.1192/bjp.140.3.292
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发表时间：
1982-01-01
影响因子：
10.5
通讯作者：
CARROLL, BJ
中科院分区：
文献类型：
--
作者：
CARROLL, BJ
许多研究人员认为忧郁症有生物学基础，生物学研究，特别是神经内分泌系统和睡眠脑电图异常的研究，现在开始产生有助于抑郁症鉴别诊断的结果。本文就地塞米松抑制试验（DST）所揭示的下丘脑-垂体-肾上腺皮质（HPA）系统的去抑制作用这一神经内分泌紊乱的研究进展作一综述。
Melancholia is thought by many investigators to have a biological basis, and biological research, particularly on abnormalities of the neuroendocrine system and of the sleep EEG, is now beginning to yield results which can help in the differential diagnosis of depressive illness. This review will focus on the most widely studied neuroendocrine disturbance: disinhibition of the hypothalamus-pituitary-adrenal cortex (HPA) system as revealed by the dexamethasone suppression test (DST).