"Referred visual sensations": rapid perceptual elongation after visual cortical deprivation.
"Referred visual sensations": rapid perceptual elongation after visual cortical deprivation.
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DOI：
10.1523/jneurosci.1557-09.2009
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发表时间：
2009-07-15
期刊：
影响因子：
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通讯作者：
Kanwisher N
中科院分区：
文献类型：
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作者：
Dilks DD;Baker CI;Liu Y;Kanwisher N
视觉感知失真（即，伸长）已经在中风后几个月的皮层剥夺后的单个病例研究中得到证实。在这里，我们问是否可以观察到类似的知觉延伸在健康的参与者后剥夺，和至关重要的是，多久后剥夺这种延伸发生。为了回答这个问题，我们修补了一只眼睛，从而非侵入性地和可逆地剥夺了自下而上输入到与未修补眼睛中的盲点（BS）相对应的初级视觉皮层（V1）区域的输入，并测试了剥夺开始后是否以及如何快速地发生延伸。在几秒钟的眼罩，参与者认为矩形相邻的BS被拉长向BS。我们将这种感知延伸归因于视网膜病变后电生理研究中报道的剥夺V1皮层内的快速感受野扩展，并将其称为“参考视觉感觉”（RVS）。这种RVS太快，不可能是皮质结构变化的结果（例如，新连接的增长），而不是暗示揭露预先存在的连接作为潜在的神经机制。这些发现可能会揭示其他报告的知觉扭曲，以及“填补”的现象。
Visual perceptual distortion (i.e., elongation) has been demonstrated in a single case study after several months of cortical deprivation following a stroke. Here we asked whether similar perceptual elongation can be observed in healthy participants following deprivation, and—crucially—how soon after deprivation this elongation occurs. To answer this question, we patched one eye, thus non-invasively and reversibly depriving bottom-up input to the region of primary visual cortex (V1) corresponding to the blind spot (BS) in the unpatched eye, and tested whether and how quickly elongation occurs after the onset of deprivation. Within seconds of eye patching, participants perceived rectangles adjacent to the BS to be elongated toward the BS. We attribute this perceptual elongation to rapid receptive field expansion within the deprived V1 cortex as reported in electrophysiological studies following retinal lesions, and refer to it as “referred visual sensations” (RVS). This RVS is too fast to be the result of structural changes in the cortex (e.g., the growth of new connections), instead implicating unmasking of pre-existing connections as the underlying neural mechanism. These findings may shed light on other reported perceptual distortions, as well as the phenomena of “filling-in”.