Secondhand smoke exposure and depressive symptoms.
Secondhand smoke exposure and depressive symptoms.
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DOI：
10.1097/psy.0b013e3181c6c8b5
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发表时间：
2010-01
影响因子：
3.3
通讯作者：
Lee DJ
中科院分区：
文献类型：
--
作者：
Bandiera FC;Arheart KL;Caban-Martinez AJ;Fleming LE;McCollister K;Dietz NA;Leblanc WG;Davila EP;Lewis JE;Serdar B;Lee DJ
探讨二手烟(SHS)暴露与抑郁症的关系。吸烟与抑郁症密切相关，但SHS的可能影响尚未得到评估。2005年至2006年全国健康和营养检查调查(NHANES)是美国非制度化平民人口的横断面样本。通过血清可替宁和患者健康问卷对20岁的≥患者的抑郁症状进行评估。通过对调查设计和潜在混杂因素的调整，完成了零膨胀泊松回归分析。在从不吸烟者中，血清可替宁记录的SHS暴露与抑郁症状呈正相关，即使在调整了年龄、种族/民族、性别、教育、饮酒和医疗合并症后也是如此。SHS暴露和抑郁症状之间的关联没有性别差异，在既往吸烟者中，SHS烟雾暴露和抑郁症状之间也没有任何关联。本研究的结果表明，在从不吸烟的人中，暴露于SHS与抑郁症状呈正相关，并强调了进一步研究的必要性，以建立联系的机制。
To evaluate the association between secondhand smoke (SHS) exposure and depression. Tobacco smoking and depression are strongly associated, but the possible effects of SHS have not been evaluated. The 2005 to 2006 National Health and Nutrition Examination Survey (NHANES) is a cross-sectional sample of the noninstitutionalized civilian U.S. population. SHS exposure was measured in adults aged ≥20 years by serum cotinine and depressive symptoms by the Patient Health Questionnaire. Zero-inflated Poisson regression analyses were completed with adjustment for survey design and potential confounders. Serum cotinine-documented SHS exposure was positively associated with depressive symptoms in never-smokers, even after adjustment for age, race/ethnicity, gender, education, alcohol consumption, and medical comorbidities. The association between SHS exposure and depressive symptoms did not vary by gender, nor was there any association between SHS smoke exposure and depressive symptoms in former smokers. Findings from the present study suggest that SHS exposure is positively associated with depressive symptoms in never-smokers and highlight the need for further research to establish the mechanisms of association.