Childhood adversity, parental vulnerability and disorder: examining inter-generational transmission of risk

Childhood adversity, parental vulnerability and disorder: examining inter-generational transmission of risk
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DOI:
10.1111/1469-7610.00234
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发表时间:
2002-11-01
影响因子:
7.6
通讯作者:
Cavagin, J
Cavagin, J
中科院分区:
医学1区
文献类型:
--
作者:
Bifulco, A;Moran, PM;Cavagin, J

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背景:对青春期晚期/成年期早期与精神障碍相关的代际因素进行了调查,以区分母亲障碍、母亲不良的心理社会功能和不良的父母教养对子女的影响。方法:样本包括一系列深入研究的276对母子,生活在相对贫穷的伦敦市中心地区,那里的单亲父母比例较高,社会经济状况较差。配对样本是在两个时间段内收集的:第一个是1985-90年连续筛查的母子系列(n=172对),第二个是1995-99年“脆弱”的母子系列(n=104对)。脆弱的母亲被选为人际功能差和/或自尊低的母亲,并使用连续的序列进行比较。观察两组儿童的儿童期逆境发生率和子女精神障碍发生率。然后,研究了母亲的特征,包括心理社会脆弱性和抑郁与风险传播的关系。结果:易患疾病母亲的子女的年精神障碍发生率是对照系列的四倍(43%比11%,P
Background: An investigation of intergenerational factors associated with psychiatric disorder in late adolescence/early adulthood was undertaken to differentiate influences from maternal disorder, maternal poor psychosocial functioning and poor parenting, on offspring. Method: The sample comprised an intensively studied series of 276 mother-offspring pairs in a relatively deprived inner-city London area with high rates of lone parenthood and socio-economic disadvantage. The paired sample was collected over two time periods: first a consecutively screened series of mothers and offspring in 1985-90 (n = 172 pairs) and second a 'vulnerable' series of mothers and offspring in 1995-99 (n = 104 pairs). The vulnerable mothers were selected for poor interpersonal functioning and/or low self-esteem and the consecutive series were used for comparison. Rates of childhood adversity and disorder in the offspring were examined in the two groups. Maternal characteristics including psychosocial vulnerability and depression were then examined in relation to risk transmission. Results: Offspring of vulnerable mothers had a fourfold higher rate of yearly disorder than those in the comparison series (43% vs. 11%, p