Skin hydration by spectroscopic imaging using multiple near-infrared bands
Skin hydration by spectroscopic imaging using multiple near-infrared bands
复制标题
使用多个近红外波段的光谱成像进行皮肤水合作用
DOI：
10.1117/12.460783
复制
发表时间：
2002
期刊：
影响因子：
2.9
通讯作者：
Shuliang L. Zhang
中科院分区：
文献类型：
--
作者：
E. M. Attas;M. Sowa;Trevor B. Posthumus;B. Schattka;H. Mantsch;Shuliang L. Zhang
近红外光谱方法已被开发用于确定人体皮肤在体内的水合程度。反射光谱成像被用来调查皮肤水分的分布作为位置的函数。在临床环境中进行的一项人体研究产生了定量数据，显示了干燥剂和保湿剂对8名志愿者前臂划定区域的影响。两个数字成像系统配备了液晶可调滤波器被用来收集堆栈的单色图像在10 nm的间隔在650-1050 nm和960-1700 nm的波长带。在三个不同的近红外波长（970，1200和1450 nm）的水吸收带面积的测量产生的图像显示出明显的差异，在皮肤中的水的表观分布。皮肤处理引起的变化在1200 nm和1450 nm图像中比在970 nm图像中明显得多。该方法在不同波长下的可变灵敏度被解释为反射率研究中使用的红外光的不同穿透深度的结果。用猪皮进行的离体实验提供了支持波长和穿透深度之间关系的证据。结合几个近红外波段的水化结果，可以获得关于水化深度的额外信息。
Near-infrared spectroscopic methods have been developed to determine the degree of hydration of human skin in vivo. Reflectance spectroscopic imaging was used to investigate the distribution of skin moisture as a function of location. A human study in a clinical setting has generated quantitative data showing the effects of a drying agent and a moisturizer on delineated regions of the forearms of eight volunteers. Two digital imaging systems equipped with liquid-crystal tunable filters were used to collect stacks of monochromatic images at 10-nm intervals over the wavelength bands 650-1050 nm and 960-1700 nm. Images generated from measurements of water absorption-band areas at three different near-IR wavelengths (970, 1200, and 1450 nm) showed obvious differences in the apparent distribution of water in skin. Changes resulting from the skin treatments were much more evident in the 1200-nm and 1450-nm images than in the 970-nm ones. The variable sensitivity of the method at different wavelengths has been interpreted as being the result of different penetration depths of the infrared light used in the reflectance studies. Ex-vivo experiments with pigskin have provided evidence supporting the relationship between wavelength and penetration depth. Combining the hydration results from several near-IR water bands allows additional information on hydration depth to be obtained.