Cross-coupling reactions catalyzed by RuHCl(CO)(PPh3)3
Cross-coupling reactions catalyzed by RuHCl(CO)(PPh3)3
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RuHCl(CO)(PPh3)3 催化的交叉偶联反应
DOI：
10.1039/d2cy01953a
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Ilhyong Ryu
中科院分区：
文献类型：
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作者：
Takahide Fukuyama;Baptiste Picard;Ilhyong Ryu
沿着它的周期表邻居，钌已被广泛探索作为催化剂，并发现拥有丰富的化学。具体来说，钌的氧化物已经引起了我们小组的注意很长一段时间，这要归功于它们可以催化的各种反应。在这篇简短的综述中，我们将总结我们在过去二十年中所做的努力，以开发新的催化方法来形成C-C键。特别地，RuHCl（CO）（PPh3）3（或简称RuH）作为市售催化剂的多功能性将通过八种不同的转化来说明。催化中涉及的基本步骤将被强调，以展示我们的机械理解与RuH的不同催化能力相结合，可以用来设计所需的催化循环，并开发新的交叉偶联反应与高原子经济。
Along with its periodic table neighbors, ruthenium has been extensively explored as a catalyst and found to possess a rich chemistry. Specifically, ruthenium hydrides have caught the attention of our group for a long time, thanks to the various reactions they can catalyze. In this minireview, we will summarize our efforts made over the last two decades toward the development of new catalytic methods for the formation of C–C bonds. In particular, the versatility of RuHCl(CO)(PPh3)3 (or RuH for short) as a commercially available catalyst will be illustrated by eight different transformations. The elementary steps involved in the catalysis will be highlighted to demonstrate how our mechanistic understanding in combination with the diverse catalytic capabilities of RuH can be used to design desired catalytic cycles and develop new cross-coupling reactions with high atom-economy.