Improvements in staging of gastric carcinoma from using the new edition of TNM classification
Improvements in staging of gastric carcinoma from using the new edition of TNM classification
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DOI：
10.1016/s0748-7983(98)93536-3
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发表时间：
1998-12-01
期刊：
影响因子：
--
通讯作者：
Hohenberger, W
中科院分区：
文献类型：
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作者：
Hermanek, P;Altendorf-Hofmann, A;Hohenberger, W
目标。目的了解第五版胃癌TNM分期与前一版相比的优势。本文分析了埃尔兰根肿瘤中心收治的898例胃癌患者行全胃或次全胃切除术及整块淋巴结清扫术的临床资料。似然比检验表明，新版TNM的预后意义有所提高。此外，第4版中固有的区域淋巴结转移的病理分类方法的不确定性现在可以避免。第5版引入的TNM分类变化得到了埃尔兰根癌症中心数据的证明，在确定N分类方面具有方法优势，并导致结局估计的改进。
Aims. To recognize possible advantages of the 5th edition of TNM of gastric carcinoma in comparison to the former edition.Methods. Data from Erlangen Cancer Center for 898 patients with gastric carcinoma treated surgically by total or subtotal gastrectomy with en bloc lymphadenectomy were analysed.Results. The prognostic significance of TNM has been improved by the new edition as demonstrated by the likelihood ratio test. In addition, uncertainties of method in the pathological classification of regional lymph-node metastasis inherent in the 4th edition can now be avoided.Conclusion. The changes in the TNM classification introduced by the 5th edition are justified by data from the Erlangen Cancer Center, have methodic advantages in determining the N classification, and lead to an improvement in estimation of outcome.