An International survey on living kidney donation and transplant practices during the COVID-19 pandemic
An International survey on living kidney donation and transplant practices during the COVID-19 pandemic
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DOI：
10.1111/tid.13526
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发表时间：
2020-12-19
影响因子：
2.6
通讯作者：
Lentine, Krista L.
中科院分区：
文献类型：
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作者：
Salvalaggio, Paolo R.;Ferreira, Gustavo F.;Lentine, Krista L.
冠状病毒病（COVID-19）大流行对全球活体肾移植（LDKT）实践的影响范围尚不明确。2020年5月至6月，我们收到了来自全球204个移植中心的关于COVID-19大流行对LDKT实践影响的调查回复。答复者来自五大洲的16个国家。总的来说，75%的应答中心报告LDKT手术被搁置（从67%的北美中心到91%的欧洲中心）。大多数（59%）的中心报告说，新的捐助者评估被停止（从46%的北美中心到86%的欧洲中心），另外23%的中心报告说，评估显著减少。只有10%的中心报告他们的评估略有不同。对于继续进行捐赠者评估的中心，40%的中心进行了亲自访问，68%的中心进行了视频访问，42%的中心进行了电话访问。在大流行期间，中心对供体（82%）和受体（76%）安全性的担忧是LDKT的主要障碍，其次是患者担忧（48%）和政府限制（46%）。欧洲中心报告说，与人员限制有关的障碍更多，而北美和拉丁美洲中心更关心的是检测能力和包括防护设备在内的资源不足。随着LDKT的恢复，96%的项目打算筛查供体和受体对是否感染冠状病毒，其中大多数是对鼻咽拭子样本进行聚合酶链反应测试。2019冠状病毒病大流行对LDKT实践的各个方面都产生了广泛影响。需要进行持续的研究和建立共识，以指导LDKT项目安全重新开放。
The scope of the impact of the Coronavirus disease 19 (COVID-19) pandemic on living donor kidney transplantation (LDKT) practices across the world is not well-defined. We received survey responses from 204 transplant centers internationally from May to June 2020 regarding the impact of the COVID-19 pandemic on LDKT practices. Respondents represented 16 countries on five continents. Overall, 75% of responding centers reported that LDKT surgery was on hold (from 67% of North American centers to 91% of European centers). The majority (59%) of centers reported that new donor evaluations were stopped (from 46% of North American centers to 86% of European centers), with additional 23% of centers reporting important decrease in evaluations. Only 10% of centers reported slight variations on their evaluations. For the centers that continued donor evaluations, 40% performed in-person visits, 68% by video, and 42% by telephone. Center concerns for donor (82%) and recipient (76%) safety were the leading barriers to LDKT during the pandemic, followed by patients concerns (48%), and government restrictions (46%). European centers reported more barriers related to staff limitations while North and Latin American centers were more concerned with testing capacity and insufficient resources including protective equipment. As LDKT resumes, 96% of the programs intend to screen donor and recipient pairs for coronavirus infection, most of them with polymerase chain reaction testing of nasopharyngeal swab samples. The COVID-19 pandemic has had broad impact on all aspects of LDKT practice. Ongoing research and consensus-building are needed to guide safe reopening of LDKT programs.