A general route to the Streptomyces-derived inthomycin family:: the first synthesis of (+)-inthomycin B
A general route to the Streptomyces-derived inthomycin family:: the first synthesis of (+)-inthomycin B
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DOI：
10.1016/j.tetlet.2005.11.042
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发表时间：
2006-01-23
影响因子：
1.8
通讯作者：
Taylor, RJK
中科院分区：
文献类型：
--
作者：
Webb, MR;Donald, C;Taylor, RJK
摘要：本文描述了一种简洁、收敛和立体控制的合成(+)-胸针素B的方法，该方法是基于苯基二烯与恶唑碘化乙烯基的Stille偶联。采用Kiyooka烯酮缩醛/氨基酸衍生的恶唑硼烷酮方法引入了不对称中心。(c) 2005 Elsevier Ltd版权所有。
94 Abstract-A concise, convergent and stereocontrolled synthesis of (+)-inthornycin B, based on the Stille coupling of a stannyl-diene with an oxazole vinyl iodide unit, is described. The asymmetric centre was introduced using the Kiyooka ketene acetal/amino acid-derived oxazaborolidinone procedure. (c) 2005 Elsevier Ltd. All rights reserved.