Addressing Parents' Vaccine Concerns: A Randomized Trial of a Social Media Intervention
Addressing Parents' Vaccine Concerns: A Randomized Trial of a Social Media Intervention
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DOI：
10.1016/j.amepre.2018.04.010
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发表时间：
2018-07-01
影响因子：
5.5
通讯作者：
Glanz, Jason M.
中科院分区：
文献类型：
--
作者：
Daley, Matthew F.;Narwaney, Komal J.;Glanz, Jason M.
引言：需要成功的策略来解决亲代疫苗犹豫，这是一个重大的公共卫生问题。本研究的目的是评估一个基于互联网的平台与疫苗信息和互动的社会媒体组件是否改善了父母的疫苗相关的attitudes.Study设计：一个三臂RCT设置/参与者：本研究是在一个大型的科罗拉多综合医疗机构进行的。父母在2013年9月至2015年10月期间入组，并随访至2016年11月;数据在2017年进行分析。在怀孕期间招募的父母在入学时接受了一项关于疫苗相关态度的调查（即，基线）以及他们的孩子年龄为3-5个月和12-15个月时（分别为时间点1和2）。干预：研究参与者被随机分配到以下网站：一个包含疫苗信息和社交媒体组件的研究网站（VSM组）;一个仅包含疫苗信息的网站（VI组）;或常规护理。主要结果测量：根据基线疫苗犹豫程度，父母疫苗态度随时间的变化。在1,093名研究参与者中，945人（86.5%）完成了所有三项调查。在疫苗犹豫的父母中，将基线与时间点1进行比较，与常规护理相比，VSM和VI组与对疫苗接种益处的态度的显著改善相关（VSM平均变化0.23（5分量表），95% CI=0.05，0.40，VI平均变化0.22，95% CI=0.04，0.40）。在犹豫不决的父母中比较基线与时间点2，与常规护理相比，VSM和VI组也与父母对疫苗接种风险的担忧显著降低相关（VSM平均变化-0.37，95% CI=-0.60，-0.14，VI平均变化-0.31，95% CI=-0.55，-0.07）。在疫苗犹豫的父母中，疫苗决策的自我效能也有所提高。没有干预效果，没有观察到在基线的父母接种疫苗犹豫不决。结论：在疫苗犹豫不决的父母，基于互联网的干预改善了父母对疫苗的态度。(C)2018年美国预防医学杂志。爱思唯尔公司出版All rights reserved.
Introduction: Successful strategies are needed to address parental vaccine hesitancy, a significant public health issue. The study objective was to assess whether an Internet-based platform with vaccine information and interactive social media components improved parents' vaccine-related attitudes.Study design: A three-arm RCT.Setting/participants: The study was conducted in a large Colorado integrated healthcare organization. Parents were enrolled during September 2013 through October 2015 and followed through November 2016; data were analyzed in 2017. Parents, recruited during pregnancy, were given a survey about vaccine-related attitudes at enrollment (i.e., baseline) and when their child was aged 3-5 months and 12-15 months (Timepoints 1 and 2, respectively). Parental vaccine hesitancy was assessed at baseline.Intervention: Study participants were randomized to the following: a study website with vaccine information and social media components (VSM arm); a website with vaccine information only (VI); or usual care.Main outcome measures: Change in parental vaccine attitudes over time by baseline degree of vaccine hesitancy.Results: Among 1,093 study participants, 945 (86.5%) completed all three surveys. Comparing baseline with Timepoint 1 among vaccine-hesitant parents, the VSM and VI arms were associated with significant improvements in attitudes regarding vaccination benefits compared to usual care (VSM mean change 0.23 on a 5-point scale, 95% CI=0.05, 0.40, VI mean change 0.22, 95% CI=0.04, 0.40). Comparing baseline with Timepoint 2 among hesitant parents, the VSM and VI arms were also associated with significant reductions in parental concerns about vaccination risks compared to usual care (VSM mean change -0.37, 95% CI= -0.60, -0.14, VI mean change -0.31, 95% CI= -0.55, -0.07). Self-efficacy around vaccine decision making also improved among vaccine-hesitant parents. No intervention effect was observed among parents not vaccine-hesitant at baseline.Conclusions: Among vaccine-hesitant parents, an Internet-based intervention improved parents' attitudes about vaccines. (C) 2018 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.