Determination of periodontal disease activity.
Determination of periodontal disease activity.
复制标题
牙周病活动度的测定。
DOI：
--
复制
发表时间：
1981
期刊：
影响因子：
--
通讯作者：
E. B. Hancock
中科院分区：
文献类型：
--
作者：
E. B. Hancock
疾病活动性的确定直接影响牙周病的治疗措施。可能表明疾病活动性的评估已在传统评估、牙周沟液含量、组织变化、循环因素和沟微生物区系等主题下进行了综述。传统的方法，如探头、X线片和临床指标，都是静态的评估，在确定疾病活动性方面的有效性有限。当用于纵向测试时，这些方法可用于回溯检测疾病活动性。评价龈沟液的含量有望成为一种非侵入性的确定牙周组织变化的方法。到目前为止，没有一种宫腔液成分是疾病活动性的可靠指标。牙周组织的变化对了解疾病过程很重要，但作为疾病活动性的指标价值有限。通过识别物质或体循环变化来确定疾病活动性的能力将被证明对临床医生非常有用。虽然一些报告发现淋巴细胞转化表明疾病活跃，但其他报告的结果却相互矛盾。最后，对牙周沟微生物区系的检查提供了证据，表明活动性牙周病与特定的病原体组和运动性微生物的数量增加有关。目前，对这些病原体和可移动生物的评估显示，最有希望确定牙周病的活动性。然而，在这种类型的评估能够被广泛接受之前，需要进行长期评估和进一步的临床试验。希望这样的研究将使临床医生能够预测活动性和非活动性牙周病的自然病史。
The determination of disease activity has a direct impact on therapeutic measures in periodontics. Evaluations that may indicate disease activity have been reviewed under the topics of traditional evaluations, gingival crevicular fluid contents, tissue changes, circulating factors, and sulcular microbiota. The traditional methods, such as probing, radiographs, and clinical indices, were static evaluations that had limited validity in determining disease activity. When used in longitudinal tests, these methods may be used retrospectively to detect disease activity. Evaluation of the contents of gingival crevicular fluid has promise as a noninvasive method of determining tissue changes in the periodontium. To date, none of the crevicular fluid constituents has been a reliable indicator of disease activity. Tissue changes in the periodontium are important in understanding the disease processes but have had limited value as indicators of disease activity. The ability to determine disease activity through identification of substances or changes in the systemic circulation would prove quite useful to the clinician. Although some reports found lymphocyte transformation indicative of active disease, others had conflicting results. Finally, examinations of sulcular microbiota provided evidence suggesting that active periodontal disease was associated with specific groups of pathogens and with elevated counts of motile organisms. The evaluation of such pathogens and motile organisms currently shows the most promise for determining periodontal disease activity. However, long-term assessments and further clinical trials are necessary before this type of evaluation can be widely accepted. It is hoped that such studies will enable the clinician to predict the natural history of active and inactive periodontal disease.