The therapeutic potential of exosomes derived from different cell sources in liver diseases
The therapeutic potential of exosomes derived from different cell sources in liver diseases
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DOI：
10.1152/ajpgi.00054.2021
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发表时间：
2022
期刊：
影响因子：
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通讯作者：
David A. Geller
中科院分区：
文献类型：
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作者：
Yun Pan;Wei-Feng Tan;Mu-Qing Yang;Ji-Yu Li;David A. Geller
Exosomes are small nanovesicles with a size of approximately 40–120 nm that are secreted from cells. They are involved in the regulation of cell homeostasis and mediate intercellular communication. In addition, they carry proteins, nucleic acids, and lipids that regulate the biological activity of receptor cells. Recent studies have shown that exosomes perform important functions in liver diseases. This review will focus on liver diseases (drug-induced liver injury, hepatic ischemia-reperfusion injury, liver fibrosis, acute liver failure, and hepatocellular carcinoma) and summarize the therapeutic potential of exosomes from different cell sources in liver disease.
