Efficacy of a Rheumatoid Arthritis-Specific Smoking Cessation Program: A Randomized Controlled Pilot Trial

Efficacy of a Rheumatoid Arthritis-Specific Smoking Cessation Program: A Randomized Controlled Pilot Trial
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DOI:
10.1002/acr.22960
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发表时间:
2017-01-01
影响因子:
4.7
通讯作者:
Stamp, Lisa K.
Stamp, Lisa K.
中科院分区:
医学2区
文献类型:
--
作者:
Aimer, Pip;Treharne, Gareth J.;Stamp, Lisa K.

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目的吸烟对类风湿性关节炎(RA)的合并症产生不利影响。这项试点研究的目的是调查针对 RA 患者进行为期 3 个月的戒烟干预后,戒烟率是否有所提高。方法 招募了 39 名患有 RA 的当前吸烟者。参与者被随机分为对照组,接受当前当地的戒烟护理标准(即 ABC = 简短建议和补贴尼古丁替代疗法 [NRT]),或进入干预组,接受 ABC 加上额外的戒烟建议,为期 3 个月 (ABC+),包括面对面、电话和电子邮件联系。建议根据参与者的具体需求,通过一系列干预工具量身定制,重点关注吸烟和 RA 教育、疼痛控制、运动、主要结果是 6 个月时戒烟。次要结果是对戒烟者和不戒烟者的疾病和心理社会特征进行了检查。结果 ABC 组和 ABC+ 组之间的戒烟率没有显着差异(21% 与 26%;P=0.70)。 (P
ObjectiveSmoking adversely influences comorbidities in rheumatoid arthritis (RA). The aim of this pilot study was to investigate whether smoking cessation is increased following a 3-month smoking cessation intervention tailored for people with RA.MethodsThirty-nine current smokers with RA were recruited. Participants were randomized into the control group to receive the current local standard of care for smoking cessation (i.e., ABC=brief advice and subsidized nicotine replacement therapy [NRT], or into the intervention group to receive ABC plus additional smoking cessation advice for 3 months (ABC+), including face-to-face, telephone, and e-mail contact. Advice was tailored to the participants' specific needs from a range of intervention tools focused on education about smoking and RA, pain control, exercise, coping, and support. The primary outcome was smoking cessation at 6 months. The secondary outcome was sustained reduction in smoking at 6 months. Disease and psychosocial characteristics of quitters and nonquitters were examined.ResultsThe overall smoking cessation rate was 24%. There was no significant difference in smoking cessation rates between the ABC and ABC+ groups (21% versus 26%; P=0.70). The mean number of cigarettes smoked daily was reduced by 44% (P