Dental caries and its relationship to bacterial infection, hypoplasia, diet, and oral hygiene in 6-to 36-month-old children
Dental caries and its relationship to bacterial infection, hypoplasia, diet, and oral hygiene in 6-to 36-month-old children
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DOI：
10.1034/j.1600-0528.2000.280408.x
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发表时间：
2000-08-01
影响因子：
2.3
通讯作者：
Bruss, J
中科院分区：
文献类型：
--
作者：
Milgrom, P;Riedy, CA;Bruss, J
Caufield等人(1)认为，幼儿感染变形链球菌最有可能发生在19至31个月大的“感染性窗口期”。目的和方法：本研究在美国北马里亚纳群岛联邦塞班岛随机抽取199名6至36个月大的儿童样本，确定龋齿和细菌感染的患病率。调查龋齿与变形链球菌感染、发育不全、饮食及口腔卫生行为的关系。结果与结论：本组儿童龋病总体患病率较高，出现白斑的占46.8%，出现牙釉质空化的占39.1%。在很小的孩子身上就可以看到殖民；在25%的儿童中检测到变形链球菌。多变量模型的结果支持了细菌感染、饮食和发育不全在该人群龋齿病因中起重要作用的假设。根据年龄和种族进行调整后，检测到高水平变形链球菌的儿童患龋齿的可能性是检测到低水平变形链球菌的儿童的5倍。发育不全和高蛀牙评分（饮食）也是显著的独立预测因素。在调整变形链球菌水平、年龄和种族后，任何发育不良的儿童患任何白斑病变或牙釉质空化的几率是得分高的儿童的9.6倍，而得分高的儿童患龋齿的几率是得分低的儿童的7.8倍。在这一人群中，与奶瓶一起睡觉、母亲共用餐具和高零食频率并不是龋齿的显著预测因素。
Caufield et al. (1) have suggested that the acquisition of mutans streptococci in young children most Likely takes place during a "window of infectivity" from 19 to 31 months of age. Objectives and Methods: This study determined the prevalence of dental caries and bacterial infection in a randomly selected sample of 199 children 6 to 36 months old from the island of Saipan in the Commonwealth of the Northern Mariana Islands, USA. The relationships between caries and Streptococcus mutans infection, hypoplasia, diet and oral hygiene behavior were investigated. Results and Conclusions: The overall estimated prevalence of caries was high: 46.8% of the children had white spot lesions and 39.1% had enamel cavitation. Colonization was seen in very young children; S. mutans was detected in 25% of the predentate children. The results of multi-variable modeling support the hypothesis that bacterial infection, diet, and hypoplasia are important in the etiology of dental caries in this population. Adjusted for age and ethnicity, children with a high level of S. mutans detected were 5 times more likely to have dental caries than children with a lower level of S. mutans detected. Hypoplasia and a high cariogenicity score (diet) were also significant independent predictors. The odds of having any white spot lesions or enamel cavitation were 9.6 times greater for children with any hypoplasia, and 7.8 times greater for children with high cariogenicity scores relative to those with lower scores after adjusting for level of S. mutans, age and ethnicity. Sleeping with a bottle, maternal sharing of utensils, and high snacking frequency were not significant predictors of caries in this population.