Echo planar MRI of the heart on a standard system: Validation of measurements of left ventricular function and mass

Echo planar MRI of the heart on a standard system: Validation of measurements of left ventricular function and mass
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DOI:
10.1097/00004728-199611000-00014
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发表时间:
1996-11-01
影响因子:
1.3
通讯作者:
deRoos, A
deRoos, A
中科院分区:
医学4区
文献类型:
--
作者:
Lamb, HJ;Doornbos, J;deRoos, A

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目的:验证多次激发平面回波磁共振(EPI)心脏测量结果,并与常规GRE技术进行比较。方法:10名健康受试者在1.5T标准MR系统上进行屏气EPI和非屏气GRE左心室短轴定位成像。获得了涵盖整个左心室的10个节段水平。测量舒张末容量(EDV)、收缩末期容量(ESV)、每搏输出量(SV)、射血分数(EF)、左心室重量、收缩末期时间(TES)和峰值充盈率(PFR)。结果:EPI的获取时间明显短于GRE(2.5min比15min)。这两种成像技术都产生了高质量的图像,从而可以进行左心室容量测量。对于EDV、SV和LV质量的测量,CRE和EPI之间的一致性最好;ESV、EF、TES和PFR的一致性较差。GRE测量TES和PFR的观察者内变异性高于EPI(单侧F检验;p=0.05的临界值为>3.18)。结论:心脏多次激发EPI能以及时有效的方式准确测量左心功能和质量。
Objective: Our goal was to validate cardiac measurements derived from multishot echo planar MRI (EPI) as compared with the well validated conventional GRE technique.Method: Ten healthy subjects underwent breath-hold EPI and non-breath-hold GRE imaging in the short axis orientation of the left ventricle (LV) on a standard 1.5 T MR system. Ten section levels were obtained to encompass the entire LV. Measurements were obtained of end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF), LV mass, time to end-systole (TES), and peak filling rate (PFR). Analysis of variance was performed to determine agreement between GRE- and EPI-derived measurements.Results: The acquisition time for EPI was much shorter than that for GRE (2.5 vs. 15 min). Both imaging techniques yielded good quality images allowing LV volumetrics. Agreement between CRE and EPI was best for measurements of EDV, SV, and LV mass; somewhat less agreement was found for ESV, EF, TES, and PFR. The intraobserver variability for measuring TES and PFR was higher for GRE than EPI (one sided F test; critical values at p = 0.05 were >3.18).Conclusion: Multishot EPI of the heart provides accurate measurements of LV function and mass in a time-efficient manner.