The melanoma 'epidemic', a dermatopathologist's perspective
The melanoma 'epidemic', a dermatopathologist's perspective
复制标题
DOI：
10.1111/j.1600-0560.2010.01660.x
复制
发表时间：
2011-03-01
影响因子：
1.7
通讯作者：
Glusac, Earl J.
中科院分区：
文献类型：
--
作者：
Glusac, Earl J.
在过去的几十年里，黑色素瘤发病率的上升被称为“流行病”。然而，对死亡率数据的详细分析表明，黑色素瘤的真实发病率并没有显著增加。皮肤病理学家在黑色素瘤的诊断中占有关键地位，他们应该对这种困境有独特的见解。导致黑色素瘤明显流行的因素可能包括密集的筛查，早期病变的采样，医疗法律压力，不完善的诊断方法以及缺乏可用的金标准。本文还探讨了明显的黑色素瘤流行的后果。
Over the past several decades, the rise in melanoma incidence has been termed "epidemic.'' However, detailed analysis of mortality data suggests that the true incidence of melanoma has not increased dramatically. Dermatopathologists, who hold a key position in the diagnosis of melanoma, should have unique insight into this quandary. Factors contributing to the apparent melanoma epidemic likely include intense screening, sampling of earlier lesions, medical-legal pressures, imperfect diagnostic methodology, and lack of a usable gold standard. Consequences of the apparent melanoma epidemic are also explored herein.