Coprescribing of opioids and high-risk medications in the USA: a cross-sectional study with data from national ambulatory and emergency department settings.
Coprescribing of opioids and high-risk medications in the USA: a cross-sectional study with data from national ambulatory and emergency department settings.
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DOI：
10.1136/bmjopen-2021-057588
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发表时间：
2022-06-16
期刊：
影响因子：
2.9
通讯作者：
Ali, Mohammed K.
中科院分区：
文献类型：
--
作者：
Suvada, Kara;Zimmer, Anna;Soodalter, Jesse;Malik, Jimi S.;Kavalieratos, Dio;Ali, Mohammed K.
描述美国阿片类药物和高风险药物共同处方的趋势。2007-2016年全国门诊医疗调查（NAMCS）和2007-2018年全国医院门诊医疗调查（NHAMCS）的连续、横断面、全国代表性数据分析。美国门诊（NAMCS）和急诊科（ED， NHAMCS）设置。在NAMCS或NHAMCS数据库中使用阿片类药物处方的18岁及以上患者就诊。阿片类药物与高危药物共同处方的频率。在2007-2018年的700 499次就诊的综合样本中，有105 720次就诊（15.1%）处方了阿片类药物。n=31 825例来自NAMCS， n=73 895例来自NHAMCS。2007年，NAMCS和NHAMCS联合样本中阿片类药物和高危药物的平均共处方率为18.4%，2014年达到峰值33.2%，2016年降至23.8%。与单独接受阿片类药物处方的成年人相比，处方阿片类药物和高风险药物的患者年龄较大，女性、白人和使用私人或医疗保险的可能性更大（p<0.0001）。共同处方在门诊比在急诊科更常见，并且一直在下降，但2016年，四分之一的阿片类药物患者就诊导致了过度处方的高风险药物。需要努力和研究来帮助降低高风险处方的比例。
Describe trends in opioid plus high-risk medication coprescribing in the USA. Analyses of serial, cross-sectional, nationally representative data of the National Ambulatory Medical Care Survey (NAMCS) over 2007–2016 and the National Hospital Ambulatory Medical Care Survey (NHAMCS) over 2007–2018. US ambulatory (NAMCS) and emergency department (ED, NHAMCS) settings. Patient visits in which the patient was 18 years and older with an opioid prescription in the NAMCS or NHAMCS databases. Frequency of opioid plus high-risk medication coprescribing. From a combined sample of 700 499 visits over 2007–2018, there were 105 720 visits (15.1%) where opioids were prescribed. n=31 825 were from NAMCS and n=73 895 were from NHAMCS. The mean prevalence of coprescription of opioids and high-risk medications for the combined NAMCS and NHAMCS sample was 18.4% in 2007, peaked at 33.2% in 2014 and declined to 23.8% in 2016. Compared with adults receiving opioid prescriptions alone, those coprescribed opioids and high-risk medications were older, more likely female, white and using private or Medicare insurance (p<0.0001). Coprescribing is more common in ambulatory than ED settings and has been declining, yet one in four patient visits where opioids were prescribed resulted in coprescribed, high-risk medications in 2016. Efforts and research to help lower the rates of high-risk prescribing are needed.
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影响因子：
3.1
作者：
Dasgupta, Nabarun;Funk, Michele Jonsson;Marshall, Steve
通讯作者：
Marshall, Steve
影响因子：
9.7
作者：
Dowell, Deborah;Zhang, Kun;Hockenberry, Jason M.
通讯作者：
Hockenberry, Jason M.
影响因子：
3.1
作者：
Cochella, Susan;Bateman, Kim
通讯作者：
Bateman, Kim
CDC规定慢性疼痛的阿片类药物的指南 - 美国，2016年。
DOI：
10.1001/jama.2016.1464
发表时间：
2016-04-19
期刊：
JAMA
影响因子：
--
作者：
Dowell D;Haegerich TM;Chou R
通讯作者：
Chou R
影响因子：
2
作者：
Heins, Sara E.;Sorbero, Mark J.;Stein, Bradley D.
通讯作者：
Stein, Bradley D.