Dark adaptation in patients with Best vitelliform macular dystrophy.
Dark adaptation in patients with Best vitelliform macular dystrophy.
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最佳卵黄样黄斑营养不良患者的暗适应。
DOI：
10.1136/bjo.78.6.430
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
Glenn,AM
中科院分区：
文献类型：
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作者：
Baca,W;Fishman,GA;Alexander,KR;Glenn,AM
采用Goldmann-Weekers暗适应仪对6例Best卵黄状黄斑营养不良（BVMD）患者进行了心理物理学暗适应研究。在获得漂白后完全恢复曲线之前，确定漂白前阈值。与Stargardt黄斑营养不良患者不同，当在临床正常外观的视网膜中进行测试时，所有BVMD患者在其视杆视色素漂白后达到其基线暗适应阈值的时间正常。虽然脂褐质材料积累在视网膜色素上皮细胞内的患者无论是最好的或Stargardt营养不良，功能的研究结果有关恢复杆暗适应阈值以及眼电图光峰暗谷比在这两种疾病是不同的。
Psychophysical dark adaptation studies were performed in six patients with Best vitelliform macular dystrophy (BVMD) using a Goldmann-Weekers dark adaptometer. Prebleach thresholds were determined before obtaining a postbleach full recovery curve. Unlike patients with Stargardt macular dystrophy, all patients with BVMD showed a normal time to reach their baseline dark adapted thresholds after bleaching of their rod visual pigment when tested in clinically normal appearing retina. Although a lipofuscin material accumulates within retinal pigment epithelial cells in patients with either Best or Stargardt dystrophy, functional findings pertaining to recovery of rod dark adaptation thresholds as well as electro-oculogram light peak to dark trough ratios are different in these two disorders.