Interfacial Lateral Electrical Conductance on Lipid Monolayer: Dose-Dependent Converse Effect of Alcohols
Interfacial Lateral Electrical Conductance on Lipid Monolayer: Dose-Dependent Converse Effect of Alcohols
复制标题
脂质单层的界面横向电导：醇的剂量依赖性逆效应
DOI：
10.1021/jp992715y
复制
发表时间：
2000
影响因子：
3.3
通讯作者：
I. Ueda
中科院分区：
文献类型：
--
作者：
T. Yoshida;and Yasutaka Koga;H. Minowa;Hiroshi Kamaya and;I. Ueda
根据二棕榈酰磷脂酰胆碱脂质体阻抗分散的温度依赖性，我们报道了氟烷降低了磷脂小泡侧面表面电导的表观活化能(Yoshida等人)。毕奇姆。生物群落。《学报》1990、1028、95；吉野等人。毕奇姆。生物群落。学报1992、1107、55)。然而，在脂质−水界面的双电层中是否存在质子流动一直是一个有争议的问题。对二维质子流的不同解释集中在实验过程中的缺陷，特别是由于单层的形成改变了电极的有效表面积而引起的电极和槽处水面的变化，局部CO2浓度引起的pH不稳定性，电极表面离子积累引起的极化，以及温度的不稳定性。我们设计了一种新型的水平板电极，完全浸入水中，以消除地层中的气体。
From the temperature dependence of the impedance dispersion in dipalmitoylphosphatidylcholine liposomes, we reported that halothane decreased the apparent activation energy of the lateral surface conductance of phospholipid vesicles (Yoshida et al. Biochim. Biophys. Acta 1990, 1028, 95; Yoshino et al. Biochim. Biophys. Acta 1992, 1107, 55). However, the presence of proton flow within the electrical double layer at the lipid−water interface has been a matter of controversy. The difference in interpretation on two-dimensional proton flow is focused on imperfection in the experimental procedure, in particular, change of the meniscus of water surface at the electrode and the trough caused by monolayer formation, which changes the effective surface area of the electrode, pH instability due to local CO2 concentrations, polarization by the accumulation of ions on the electrode surface, and temperature instability. We designed a novel horizontal-plate electrode, totally immersed in water, to eliminate formation o...