A composite resonator assembly suitable for EPR/NMR coregistration imaging
A composite resonator assembly suitable for EPR/NMR coregistration imaging
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DOI：
10.1002/cmr.b.20028
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发表时间：
2005-04-01
影响因子：
0.9
通讯作者：
Utsumi, H
中科院分区：
文献类型：
--
作者：
Matsumoto, S;Nagai, M;Utsumi, H
描述了用于电子顺磁共振 (EPR)/核磁共振 (NMR) 成像的复合谐振器组件的开发及其在 EPR/NMR 配准成像中的首次应用。解剖配准对于通过体内自由基分布的 EPR 对图像进行有意义的解释是有用的。复合谐振器组件由并联线圈谐振器、用于 EPR 成像的场调制线圈和用于 NMR 成像的螺线管检测线圈组成。 EPR 成像还使用射频 (RF) 屏蔽。使用小环天线对EPR谐振器的射频磁场的均匀性进行了实验测量；它沿长轴和径向平面相当均匀。 EPR 和 NMR 图像是通过模型和动物测试获得的。并联线圈谐振器的存在并没有显着影响 NMR 图像。使用三个位置标记计算自由基和质子分布的叠加。该组件执行两个多模态图像的配准。它与开放式临床 NMR 成像仪的正交交叉线圈配置兼容。 (c) 2005 年 Wiley 期刊公司。
The development of a composite resonator assembly for electron paramagnetic resonance (EPR)/nuclear magnetic resonance (NMR) imaging and its first application to EPR/NMR coregistration imaging are described. Anatomic registration would be useful for the meaningful interpretation of images by EPR of free radical distributions in vivo. The composite resonator assembly consists of a parallel coil resonator, a field modulation coil for EPR imaging, and a solenoidal detection coil for NMR imaging. Radio-frequency (RF) shielding was used in addition for the EPR imaging. The homogeneity of the RF magnetic field of the EPR resonator was measured experimentally using a small-loop antenna; it was reasonably homogeneous along the long axis and in the radial plane. EPR and NMR images were obtained with both phantom and animal tests. The presence of the parallel coil resonator did not significantly affect NMR images. The superposition of the distribution of free radicals and protons was computed using three positional markers. The assembly performs the registration of two multimodal images. It is compatible with an orthogonal crossed-coil configuration for open-type clinical NMR imagers. (c) 2005 Wiley Periodicals, Inc.