Bacteraemia due to tribe proteeae: A review of 132 cases during a decade (1991-2000)
Bacteraemia due to tribe proteeae: A review of 132 cases during a decade (1991-2000)
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DOI：
10.1080/0036554021000027015
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发表时间：
2003-01-01
影响因子：
--
通讯作者：
Ryu, JS
中科院分区：
文献类型：
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作者：
Kim, BN;Kim, NJ;Ryu, JS
为探讨变形菌菌血症的临床特点，对1991 ~ 2000年130例变形菌菌血症患者中132例进行了分析。其中变形杆菌属63例（奇异变形杆菌41例，围栏变形杆菌2例，普通变形杆菌20例），普罗威登斯菌属8例（雷氏普罗威登斯菌3例，斯氏普罗威登斯菌5例），摩氏摩根菌61例。细菌性摩根菌感染以院内感染多见（70.5%）。摩根菌血症以胆道和肝脏疾病为主，变形杆菌血症以心血管、泌尿系统和神经系统疾病为主。在摩根氏菌感染的病例中更常放置胆道引流管（39.3%，p < 0.001），在变形杆菌感染的病例中更常放置导尿管（17.5%）。胆系感染以摩根菌属菌血症最多见（49.2%），而尿路感染以变形杆菌菌血症最多见（47.6%）。与变形菌族引起的细菌性贫血直接相关的死亡率为20.8%（变形杆菌属、普罗维登西亚菌属和细菌性摩根菌属分别为22.6%、50.0%和15.0%）。总之，摩根菌菌血症最常与胆道感染相关，而变形杆菌菌血症最常与UTI相关。普罗维登菌菌血症是相对罕见的，它可以与感染以外的尿路感染。
To characterize the clinical features of bacteraemia due to tribe Proteeae, 132 cases among 130 patients from 1991 to 2000 were analysed. The organisms included the Proteus species in 63 cases (P. mirabilis in 41, P. penned in 2 and P. vulgaris in 20), the Providencia species in 8 (P. rettgeri in 3 and P. stuartii 5) and Morganella morganii in 61. Morganella bacteraernia occurred more frequently in the hospital (70.5%). Biliary and hepatic diseases were predominant in cases with Morganella bacteraemia while cardiovascular, urological and neurological diseases were more common in cases with Proteus bacteraernia. Biliary drainage catheters had more frequently been placed in cases with Morganella bacteraernia (39.3%, p < 0.001), and urinary catheters more frequently in cases with Proteus bacteraernia (17.5%). Biliary infection was most common in cases with Morganella bacteraemia (49.2%), while urinary tract infection (UTI) was most common in cases with Proteus bacteraernia (47.6%). Mortality directly related to bacteraernia due to tribe Proteeae was 20.8% (22.6, 50.0 and 15.0% for Proteus, Providencia and Morganella bacteraernia, respectively). In conclusion, Morganella bacteraemia was most frequently associated with biliary infection, while Proteus bacteraernia was most frequently with UTI. Providencia bacteraernia was relatively uncommon and it can be associated with infections other than UTI.