p53 Protects Cells from Death at the Heatstroke Threshold Temperature
p53 Protects Cells from Death at the Heatstroke Threshold Temperature
复制标题
p53 保护细胞在中暑阈值温度下免于死亡。
DOI：
10.1016/j.celrep.2019.11.032
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发表时间：
2019-12-10
期刊：
影响因子：
8.8
通讯作者：
Chen, Jun
中科院分区：
文献类型：
--
作者：
Gong, Lu;Zhang, Qinghe;Chen, Jun
当核心体温高于40摄氏度时，就会因中暑而威胁生命。肿瘤阻遏物p53是在高温条件下（>41摄氏度）热诱导的细胞凋亡所必需的。然而，它在亚中暑条件下的作用（
When the core body temperature is higher than 40 degrees C, life is threatened due to heatstroke. Tumor repressor p53 is required for heat-induced apoptosis at hyperthermia conditions (>41 degrees C). However, its role in sub-heatstroke conditions (