Perspectives from the Society for Pediatric Research: Probiotic use in urinary tract infections, atopic dermatitis, and antibiotic-associated diarrhea: an overview.

Perspectives from the Society for Pediatric Research: Probiotic use in urinary tract infections, atopic dermatitis, and antibiotic-associated diarrhea: an overview.
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小儿研究学会的观点:尿路感染,特应性皮炎和抗生素相关的腹泻的益生菌使用:概述。

DOI:
10.1038/s41390-020-01298-1
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发表时间:
2021-08
期刊:
影响因子:
3.6
通讯作者:
Cabana MD
Cabana MD
中科院分区:
医学3区
文献类型:
--
作者:
Forster CS;Hsieh MH;Cabana MD

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益生菌因其潜在的促进健康的特性,包括治疗或预防儿童的各种疾病,在科学界和非专业界都受到了极大的关注。在这篇文章中,我们回顾了已发表的关于使用特定益生菌菌株治疗三种常见儿科疾病的数据:预防尿路感染和腹泻相关性腹泻以及治疗特应性皮炎。对特定益生菌菌株效用的研究质量参差不齐,数据通常来自小型研究和病例系列。我们讨论了这些研究的科学价值,关于益生菌在这些适应症中的效用的总体发现,方法报告中的问题,这些临床试验的结果,以及未来的研究领域。审查一般儿科人群中常见诊断的数据。突出证据的差距,并提供深入了解新的研究途径。
Probiotics have received significant attention within both the scientific and lay communities for their potential health-promoting properties, including the treatment or prevention of various conditions in children. In this article, we review the published data on use of specific probiotic strains for three common pediatric conditions: the prevention of urinary tract infections and antibiotic-associated diarrhea and the treatment of atopic dermatitis. Research into the utility of specific probiotic strains is of varying quality, and data are often derived from small studies and case series. We discuss the scientific merit of these studies, their overall findings regarding the utility of probiotics for these indications, issues in reporting of methods, and results from these clinical trials, as well as future areas of investigation. Review of data for commonly encountered diagnoses in the general pediatric population. Highlights gaps in the evidence and provides insight into new avenues of research.
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