Characterizing emotional dysfunction in borderline personality, major depression, and their co-occurrence
Characterizing emotional dysfunction in borderline personality, major depression, and their co-occurrence
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DOI：
10.1016/j.comppsych.2015.07.014
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发表时间：
2015-10-01
影响因子：
7.3
通讯作者：
Gratz, Kim L.
中科院分区：
文献类型：
--
作者：
Dixon-Gordon, Katherine L.;Weiss, Nicole H.;Gratz, Kim L.
本研究旨在探讨边缘型人格、抑郁症及其共病者的情绪反应和失调模式。在研究1中，488名来自社区的年轻成年女性根据自我报告的重度抑郁症（MDD）和边缘型人格障碍（BPD）症状分为四组（低BPD/低MDD;低BPD/高MDD;高BPD/低MDD;高BPD/高MDD）。对实验室压力源的即时和长期主观情绪反应进行了评估，参与者完成了情绪失调的自我报告和行为测量。研究2扩展了这些研究结果，研究了176名诊断为BPD和MDD的物质依赖患者的临床人群中的情绪反应和失调，并包括情绪反应的生物学指标。结果显示，在研究1中，高BPD/高MDD组（与低BPD/低MDD组相比）的长期恐惧反应更大，在研究2中，高BPD组（与低BPD/低MDD组和低BPD/高MDD组相比）的长期焦虑和负面情绪反应更大（但皮质醇反应没有差异）。结果还表明，研究1中的高BPD/高MDD组（与低BPD/低MDD组相比）和研究2中的两个高BPD组（与两个低BPD组相比）的主观（但非行为）情绪失调更严重。最后，与研究1中的所有其他组和研究2中的低BPD组相比，高BPD/高MDD组报告了更大的控制冲动行为的困难。研究结果表明，BPD病理（但不是MDD病理单独）的特点是更大的长期情绪（特别是焦虑/恐惧相关）反应和情绪失调加剧。(C)2015 Elsevier Inc. All rights reserved.
This research aimed to characterize patterns of emotional reactivity and dysregulation in borderline personality, depression, and their co-occurrence. In study 1, 488 young adult women from the community were categorized into four groups based on self-reported major depressive disorder (MDD) and borderline personality disorder (BPD) symptoms (Low BPD/Low MDD; Low BPD/High MDD; High BPD/Low MDD; High BPD/High MDD). Immediate and prolonged subjective emotional reactivity to a laboratory stressor were assessed, and participants completed self-report and behavioral measures of emotion dysregulation. Study 2 extended these findings, examining emotional reactivity and dysregulation in a clinical population of 176 substance dependent patients with diagnoses of BPD and MDD and including a biological index of emotional reactivity. Results revealed greater prolonged fear reactivity in the High BPD/High MDD (vs. Low BPD/Low MDD) group in study 1, and greater prolonged anxiety and negative affect reactivity in both High BPD groups (vs. Low BPD/Low MDD and Low BPD/High MDD groups) in study 2 (but no differences in cortisol reactivity). Results also demonstrated greater subjective (but not behavioral) emotion dysregulation in the High BPD/High MDD (vs. Low BPD/Low MDD) group in study 1 and both High BPD groups (vs. both Low BPD groups) in study 2. Finally, the High BPD/High MDD group reported greater difficulties controlling impulsive behaviors compared with all other groups in study 1 and the Low BPD groups in study 2. Findings suggest that BPD pathology (but not MDD pathology alone) is characterized by greater prolonged emotional (especially anxiety/fear-related) reactivity and heightened emotion dysregulation. (C) 2015 Elsevier Inc. All rights reserved.