New technologies in cervical cytology screening: A word of caution
New technologies in cervical cytology screening: A word of caution
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DOI：
10.1016/s0029-7844(99)00289-6
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发表时间：
1999-08-01
影响因子：
7.2
通讯作者：
Grimes, DA
中科院分区：
文献类型：
--
作者：
Sawaya, GF;Grimes, DA
今年，美国将有近5000名女性死于宫颈癌，其中许多死亡是可以预防的。大多数病例(60%)与缺乏或缺乏筛查有关。大约25%的筛查失败是由于宫颈采样或涂片解读的错误。尽管科学评估有限，但细胞学筛查的新技术，如基于液体的涂片和载玻片的计算机重新筛选，正在向医生和普通公众推广。提高筛查测试的有效性很重要，但为此目的转移资源可能会造成净伤害，如果结果是高危妇女的筛查机会减少。新的筛查技术无法解决这一利用差距，并可能通过将筛查成本推高至高危妇女负担不起而扩大这一差距。如果将同样的资源投入到针对高危女性的全面全国筛查计划中，宫颈癌发病率和死亡率可能会有更大的下降。(C)1999年，由美国妇产科医师学会提供。
Nearly 5000 women in the United States will die of cervical cancer this year and many of those deaths could be prevented. Most incident cases (60%) are associated with absent or deficient screening. Approximately 25% of screening failures are due to errors in cervical sampling or smear interpretation. New techniques for cytology screening such as liquid-based smears and computerized rescreening of slides are being promoted to physicians and the lay public despite limited scientific evaluation. Improving the validity of screening tests is important, but shifting resources for this purpose might cause net harm if the result is fewer screening opportunities for high-risk women. New screening technologies do not address this utilization gap and might widen it by driving the cost of screening out of the reach of high-risk women. Greater decreases in cervical cancer morbidity and mortality would likely result if the same resources were invested in a comprehensive national screening program that targeted women at highest risk. (C) 1999 by The American College of Obstetricians and Gynecologists.