The morphometry of soft tissue insertions on the tibial plateau: data acquisition and statistical shape analysis.

The morphometry of soft tissue insertions on the tibial plateau: data acquisition and statistical shape analysis.
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DOI:
10.1371/journal.pone.0096515
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发表时间:
2014
期刊:
影响因子:
3.7
通讯作者:
Zhang X
Zhang X
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Zheng L;Harner CD;Zhang X

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本研究对胫骨平台软组织插入形态计量学及其相互关系和变异性进行了研究。将20例尸体胫骨(10例左膝和10例右膝)的十字韧带和半月板根插入点以及内侧和外侧软骨的轮廓进行数字化,并与相应的基于ct的3D骨模型共同注册。将广义Procrustes分析与主成分分析结合使用,首先建立基于胫骨软骨的几何共识,然后确定插入形态计量学的均值和变化,包括形状、大小、位置和相互关系测量。采用逐步回归分析,寻找形态测量指标与胫骨平台宽度和深度、基本人体测量和性别因素之间的简洁模型。分析结果显示,重叠交叉韧带和半月板插入处具有统计学形态计量学表征,仅发现少数中度相关性(R: 0.37-0.49)。该研究为相关形态学研究中经常使用的基于单一维度的等长尺度提供了挑战证据,并为评估十字韧带重建策略提供了数据,以重建原始解剖结构并最大限度地减少医源性损伤的风险。它为计算机辅助个性化骨科手术应用的未来发展铺平了道路,提高了护理质量和患者安全,以及具有更好的人口或平均代表性的生物力学模型。
This study characterized the soft tissue insertion morphometrics on the tibial plateau and their inter-relationships as well as variabilities. The outlines of the cruciate ligament and meniscal root insertions along with the medial and lateral cartilage on 20 cadaveric tibias (10 left and 10 right knees) were digitized and co-registered with corresponding CT-based 3D bone models. Generalized Procrustes Analysis was employed in conjunction with Principal Components Analysis to first create a geometric consensus based on tibial cartilage and then determine the means and variations of insertion morphometrics including shape, size, location, and inter-relationship measures. Step-wise regression analysis was conducted in search of parsimonious models relating the morphometric measures to the tibial plateau width and depth, and basic anthropometric and gender factors. The analyses resulted in statistical morphometric representations for Procrustes-superimposed cruciate ligament and meniscus insertions, and identified only a few moderate correlations (R 2: 0.37–0.49). The study provided evidence challenging the isometric scaling based on a single dimension frequently employed in related morphometric studies, and data for evaluating cruciate ligament reconstruction strategies in terms of re-creating the native anatomy and minimizing the risk of iatrogenic injury. It paved the way for future development of computer-aided personalized orthopaedic surgery applications improving the quality of care and patient safety, and biomechanical models with a better population or average representation.
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