Chronic stress and emotion: Differential effects on attentional processing and recognition memory
Chronic stress and emotion: Differential effects on attentional processing and recognition memory
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DOI：
10.1016/j.psyneuen.2019.05.008
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发表时间：
2019-09
影响因子：
3.7
通讯作者：
Janine Wirkner;C. Ventura-Bort;L. Schwabe;A. Hamm;M. Weymar
中科院分区：
文献类型：
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作者：
Janine Wirkner;C. Ventura-Bort;L. Schwabe;A. Hamm;M. Weymar
先前的研究表明，学习期间的急性压力有助于注意和记忆情感上显着的信息。尽管这些急性应激效应的证据越来越多，但对慢性应激的作用知之甚少。因此，在本研究中，我们使用头发皮质醇浓度作为慢性压力的生物标志物，测试了女性参与者的情绪和中性场景处理以及后来的识别记忆。事件相关电位在图片观看过程中记录表明，增强晚正电位（LPPs）的情绪，相对于中性的内容。这些脑电位的变化作为长期的头发皮质醇水平的函数：头发皮质醇水平呈正相关的整体LPP幅度。编码后一周的识别记忆测试结果显示，相对于中性场景，情感记忆更好。然而，头发皮质醇水平与较差的记忆准确性有关。综上所述，我们的研究结果表明，慢性应激增强了对新刺激的编码过程中的注意加工，并损害了后来的再认记忆。结果讨论了慢性应激对某些大脑区域的相反影响（例如，杏仁核和海马体）。
Previous research indicates that acute stress around the time of learning facilitates attention and memory for emotionally salient information. Despite accumulating evidence for these acute stress effects, less is known about the role of chronic stress. In the present study, we therefore tested emotional and neutral scene processing and later recognition memory in female participants using hair cortisol concentrations as a biological marker for chronic stress. Event-related potentials recorded during picture viewing indicated enhanced late positive potentials (LPPs) for emotional, relative to neutral contents. These brain potentials varied as a function of long-term hair cortisol levels: hair-cortisol levels were positively related to overall LPP amplitudes. Results from recognition memory testing one week after encoding revealed better memory for emotional relative to neutral scenes. Hair-cortisol levels, however, were related to poorer memory accuracy. Taken together, our results indicate that chronic stress enhanced attentional processing during encoding of new stimuli and impaired later recognition memory. Results are discussed with regard to putatively opposite effects of chronic stress on certain brain regions (e.g., amygdala and hippocampus).