Theoretical and Experimental Studies of Epidermal Heat Flux Sensors for Measurements of Core Body Temperature.
Theoretical and Experimental Studies of Epidermal Heat Flux Sensors for Measurements of Core Body Temperature.
复制标题
DOI：
10.1002/adhm.201500110
复制
发表时间：
2016-01-07
影响因子：
10
通讯作者：
Rogers JA
中科院分区：
文献类型：
--
作者：
Zhang Y;Webb RC;Luo H;Xue Y;Kurniawan J;Cho NH;Krishnan S;Li Y;Huang Y;Rogers JA
由于核心体温作为临床判断和患者管理的关键生物医学信号被广泛使用，因此长期连续测量核心体温具有很高的意义。传统的方法依赖于刚性和平面形式的装置或仪器，不容易与皮肤的柔软、曲线、时间动态的表面紧密或贴合地整合。这里，提出了用于差温传感器的材料和机械设计，其可以柔软且可逆地附接到皮肤表面上，并且还维持高水平的变形（例如，弯曲、扭曲和拉伸）。理论方法与建模算法一起，从与皮肤相距不同有效距离的温度传感器的多个差分测量值产生核心体温。通过有限元分析（FEA）分析灵敏度、准确度和响应时间，为传感器设计和性能之间的关系提供指导方针。在不同尺寸和不同对流条件下的多个设备上进行的四组实验说明了该技术和分析方法的关键特征。最后，结果表明，具有蜂窝结构的隔热材料在减少响应时间和提高精度方面具有优势，同时改善了机械性能和透气性。
Long-term, continuous measurement of core body temperature is of high interest, due to the widespread use of this parameter as a key biomedical signal for clinical judgment and patient management. Traditional approaches rely on devices or instruments in rigid and planar forms, not readily amenable to intimate or conformable integration with soft, curvilinear, time-dynamic, surfaces of the skin. Here, materials and mechanics designs for differential temperature sensors are presented which can attach softly and reversibly onto the skin surface, and also sustain high levels of deformation (e.g., bending, twisting, and stretching). A theoretical approach, together with a modeling algorithm, yields core body temperature from multiple differential measurements from temperature sensors separated by different effective distances from the skin. The sensitivity, accuracy, and response time are analyzed by finite element analyses (FEA) to provide guidelines for relationships between sensor design and performance. Four sets of experiments on multiple devices with different dimensions and under different convection conditions illustrate the key features of the technology and the analysis approach. Finally, results indicate that thermally insulating materials with cellular structures offer advantages in reducing the response time and increasing the accuracy, while improving the mechanics and breathability.