Experimental evolution of local parasite maladaptation
Experimental evolution of local parasite maladaptation
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DOI：
10.1111/j.1420-9101.2010.01985.x
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发表时间：
2010-06-01
影响因子：
2.1
通讯作者：
Kaltz, O.
中科院分区：
文献类型：
--
作者：
Adiba, S.;Huet, M.;Kaltz, O.
在宿主-寄生虫系统中，局部适应的标志和程度可能因生态、流行病学或遗传参数而异。为了探讨宿主遗传背景的作用，我们建立了长期的实验种群的不同基因型的原生动物草履虫尾，感染细菌寄生虫Holospora undulata。我们观察到寄生虫局部适应不良的感染性的整体模式的演变，表明这种寄生虫的一般共同进化的缺点。适应不良扩展到具有相同遗传背景的宿主种群，类似于自然种群从本地扩展到更高的区域水平。毒力模式定性相似，但统计支持较少。一个不显着的相关性与水平的（错误）适应感染性表明独立的这些特征的演变。我们的研究结果表明，在不同的遗传背景的人群相似的（共）进化轨迹。尽管如此，遗传距离和寄生虫性能的相关倾斜说明了遗传背景如何塑造局部适应的空间梯度。
Sign and magnitude of local adaptation in host-parasite systems may vary with ecological, epidemiological or genetic parameters. To investigate the role of host genetic background, we established long-term experimental populations of different genotypes of the protozoan Paramecium caudatum, infected with the bacterial parasite Holospora undulata. We observed the evolution of an overall pattern of parasite local maladaptation for infectivity, indicating a general coevolutionary disadvantage of this parasite. Maladaptation extended to host populations with the same genetic background, similar to extending from the local to a higher regional level in natural populations. Patterns for virulence were qualitatively similar, but with less statistical support. A nonsignificant correlation with levels of (mal)adaptation for infectivity suggests independent evolution of these traits. Our results indicate similar (co)evolutionary trajectories in populations with different genetic backgrounds. Nonetheless, the correlated clines of genetic distance and parasite performance illustrate how genetic background can shape spatial gradients of local adaptation.