Allowing for within-subpopulation inbreeding in forensic match probabilities

Allowing for within-subpopulation inbreeding in forensic match probabilities
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DOI:
10.1016/s0379-0738(99)00087-0
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发表时间:
1999-09-09
影响因子:
2.2
通讯作者:
Overall, ADJ
Overall, ADJ
中科院分区:
医学3区
文献类型:
--
作者:
Ayres, KL;Overall, ADJ

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在计算法医匹配概率时,允许最近的共同祖先的重要性已经被认可了一段时间。亚群内的近亲繁殖也会影响匹配概率,忽略这些影响可能会导致对被告的DNA证据强度的夸大。然而,近亲繁殖可以很容易地占在匹配概率,将近亲繁殖系数F-IS到计算。我们推导出必要的公式,并证明了包括F-IS(除了F-ST)的方程的效果。(C)1999爱思唯尔科学爱尔兰有限公司保留所有权利。
The importance of allowing for recent shared ancestry when calculating forensic match probabilities has been recognised for some time. Within-subpopulation inbreeding will also affect the match probability, and ignoring these effects can lead to an overstatement of the strength of the DNA evidence against a defendant. However, inbreeding can be readily accounted for in match probabilities by incorporating the inbreeding coefficient F-IS into calculations. We derive the necessary formulae, and demonstrate the effect of including F-IS (in addition to F-ST) in the equations. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.