[Renal involvement in connective tissue diseases].
[Renal involvement in connective tissue diseases].
复制标题
[结缔组织疾病中的肾脏受累]。
DOI：
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发表时间：
2009
期刊：
影响因子：
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通讯作者：
S. Ito
中科院分区：
文献类型：
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作者：
S. Ito
结缔组织疾病如系统性红斑狼疮或系统性硬化症的肾脏受累的预后由于新的免疫抑制剂如他克莫司和降低肾小球高血压的低渗剂如血管紧张素转换酶抑制剂或血管紧张素II受体拮抗剂的诱导而变得更好。由于髓过氧化物酶-抗中性粒细胞胞浆抗体相关性肾小球肾炎患者比韦格纳肉芽肿患者年龄大，因此应避免西方国家推荐的强免疫抑制治疗。日本肾脏病学会发布的治疗指南适用于日本老年患者。最近，有一些使用咪唑立宾的报道，咪唑立宾是一种温和的免疫抑制剂。
Prognosis of the renal involvement of connective tissue diseases such as systemic lupus erythematosus or systemic sclerosis is getting better due to the induction of the new immunosuppressant such as tacrolimus and hypotonicas which reduce glomerular hypertension such as angiotensin converting enzyme inhibitor or angiotensin II receptor antagonist. Since patients with myeloperoxidase-anti-neutrophil cytoplasmic antibody related glomerulonephritis are older than those with Wegener's granulomatosis, the strong immunosuppressive treatment recommended in Western countries should be avoided. The treatment guideline issued by the Japanese Society of Nephrology is suitable for elderly Japanese patients. Recently, there have been some reports of the use of mizoribine, which is a mild immunosuppressant drug.