Alcohol involvement as a function of co-occurring alcohol use disorders and major depressive episode: Evidence from the National Epidemiologic Survey on Alcohol and Related Conditions
Alcohol involvement as a function of co-occurring alcohol use disorders and major depressive episode: Evidence from the National Epidemiologic Survey on Alcohol and Related Conditions
复制标题
DOI：
10.1016/j.drugalcdep.2011.01.011
复制
发表时间：
2011-09-01
影响因子：
4.2
通讯作者：
Zucker, Robert A.
中科院分区：
文献类型：
--
作者：
Cranford, James A.;Nolen-Hoeksema, Susan;Zucker, Robert A.
背景：酒精使用障碍和重度抑郁症(C-ALDP)是一个重大的公共卫生问题。然而，关于C-ALDP对酒精参与的影响，现有的证据是混合的。这项研究的目的是在一个具有代表性的社区样本中检查过去12个月共发生的AUDS(滥用和依赖)和严重抑郁发作(MDE)与酒精参与之间的关系。设计：国家酒精及相关条件流行病学调查(NESARC)是一项全国性的家庭调查，调查对象为43,093名18岁及以上的成年人。NESARC的目标人群是居住在美国和哥伦比亚区的18岁及以上的平民非住院人口。方法：所有的访谈都是根据酒精使用障碍和相关残疾访谈量表-DSM IV版本(AUDADIS-IV；Grant等人，2003a)进行的。结果：过去12个月同时发生AUD(虐待或依赖)和MDE的患病率为1.2%，相当于约240万18岁及以上的成年人。在有酒精依赖的男性中，MDE的共病与独自在家饮酒的天数更多有关。在酗酒和依赖的女性和男性中，MDE的共病与更高的饮酒率相关，以增强抑郁情绪。在酗酒者中，共病的MDE也与较低的饮酒行为水平相关。结论：共同发生的AUDS和MDE与酒精参与的特定维度相关，这种关联在酒精依赖方面比在滥用方面更一致。(C)2011爱思唯尔爱尔兰有限公司。保留所有权利。
Background: Co-occurring alcohol use disorder and major depression (C-ALDP) is a major public health problem. Yet, the available evidence is mixed regarding the implications of C-ALDP for alcohol involvement. The purpose of this research was to examine the associations between past 12-month co-occurring AUDs (abuse and dependence) and major depressive episode (MDE) and alcohol involvement in a representative community sample.Design: The National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) is a national household survey of 43,093 adults ages 18 and older. For the NESARC, the target population is the civilian noninstitutionalized population, 18 years of age and older, living in the United States and the District of Columbia.Methods: All NESARC interviews were conducted with the Alcohol Use Disorder and Associated Disabilities Interview Schedule - DSM IV Version (AUDADIS-IV; Grant et al., 2003a).Results: Prevalence of past 12-month co-occurring AUD (abuse or dependence) and MDE was 1.2%, corresponding to about 2.4 million adults ages 18 and older. Among males with alcohol dependence, comorbid MDE was associated with a greater number of days drinking at home alone. Among females and males with alcohol abuse and dependence, comorbid MDE was associated with higher prevalence of drinking to enhance depressed mood. Comorbid MDE was also associated with lower levels of some drinking behaviors among those with alcohol abuse.Conclusions: Co-occurring AUDs and MDE are associated with specific dimensions of alcohol involvement, and this association is more consistent for alcohol dependence than abuse. (C) 2011 Elsevier Ireland Ltd. All rights reserved.