Frailty-associated dysbiosis of human microbiotas in older adults in nursing homes.
Frailty-associated dysbiosis of human microbiotas in older adults in nursing homes.
复制标题
疗养院老年人与虚弱相关的人类微生物群失调。
DOI：
10.1038/s43587-022-00289-7
复制
发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Kuchel,GeorgeA
中科院分区：
文献类型：
--
作者：
Oh,Julia;Robison,Julie;Kuchel,GeorgeA
我们的纵向研究比较了社区居民老年人和养老院居民的皮肤，肠道和口服微生物组，显示出惊人的变化与抗生素耐药性和疾病风险有关。这种转变与脆弱的，而不是年代年龄有关，并且在皮肤中最为明显，这是感染风险的主要储层。
Our longitudinal study comparing the skin, gut and oral microbiomes of community-dwelling older adults and nursing home residents showed striking changes known to be linked to antibiotic resistance and disease risk. Such shifts were associated with frailty, not chronological age, and were most pronounced in the skin, the primary reservoir for infection risk.