Pain after uterine fibroid embolisation is associated with the severity of myometrial ischaemia on magnetic resonance imaging
Pain after uterine fibroid embolisation is associated with the severity of myometrial ischaemia on magnetic resonance imaging
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DOI：
10.1007/s00330-009-1481-8
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发表时间：
2009-12-01
影响因子：
5.9
通讯作者：
Manninen, Hannu
中科院分区：
文献类型：
--
作者：
Ruuskanen, Anu;Sipola, Petri;Manninen, Hannu
本研究的目的是使用磁共振成像评价子宫动脉栓塞术（UAE）后的子宫缺血以及子宫肌层和肌瘤缺血在术后疼痛发病机制中的作用。对62例女性患者在UAE术前及术后24 h分别进行对比剂前后T1加权梯度回波成像。我们评估了子宫肌层缺血的严重程度（轻度、中度、重度），以及子宫肌层和肌瘤中缺血组织的百分比和体积。使用语言评定量表评估住院术后疼痛（1-3轻度，4-6中度，7-10重度）。平均最大疼痛为7.7。轻度、中度和重度子宫肌层缺血分别为29例、23例和10例。中度或重度子宫肌层缺血（p = 0.041）、子宫肌层中缺血组织的百分比（p = 0.037）和体积（p = 0.012）以及大量栓塞材料（p = 0.038）与重度疼痛相关。总之，子宫动脉栓塞后疼痛是常见的，部分原因是子宫肌层缺血。
The purpose of the study was to evaluate uterine ischaemia after uterine artery embolisation (UAE) using magnetic resonance imaging and the role of myometrial and fibroid ischaemia in the pathogenesis of post-procedural pain. T1-weighted gradient echo imaging before and after contrast agent was performed on 62 women before and 24 h after UAE. We assessed the severity (mild, moderate, severe) of myometrial ischaemia, and the percentage and volume of ischaemic tissue in myometrium and fibroids. The Verbal Rating Scale was used to assess in-hospital post-procedural pain (1-3 mild, 4-6 moderate, 7-10 severe). Mean maximal pain was 7.7. Myometrial ischaemia was mild, moderate and severe in 29, 23 and 10 patients, respectively. Moderate or severe myometrial ischaemia (p = 0.041), the percentage (p = 0.037) and volume (p = 0.012) of ischaemic tissue in the myometrium, and a large volume of embolic material (p = 0.038) correlated with severe pain. In summary, pain following UAE is common and partly explained by myometrial ischaemia.