Body side of motor symptom onset in Parkinson's disease is associated with memory performance
Body side of motor symptom onset in Parkinson's disease is associated with memory performance
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DOI：
10.1017/s1355617706060875
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发表时间：
2006-09-01
影响因子：
2.6
通讯作者：
Chou, K. L.
中科院分区：
文献类型：
--
作者：
Amick, M. M.;Grace, J.;Chou, K. L.
研究了帕金森病（PD）运动症状发作的体侧与半球优势相关的记忆测量的关系。对14例右侧体侧运动症状发作（RPD，推断左半球功能障碍）和16例左侧发作（LPD，右半球功能障碍）的患者进行了言语（霍普金斯言语学习测试修订版）和视觉记忆（简要视觉记忆测试修订版）的测量，这需要类似的任务要求，并分别与左半球或右半球优势相关。无论是组内还是与RPD组相比，LPD组的视觉记忆都比言语记忆差。相比之下，RPD组在组内表现出比视觉记忆更差的言语记忆。这些发现表明，运动症状发作的一侧与不对称记忆功能障碍有关。
The relation of body side of motor symptom onset in Parkinson's disease (PD) to memory measures associated with hemispheric dominance was examined. Fourteen patients with right body side motor symptom onset (RPD, inferred left hemisphere dysfunction) and 16 patients with left side onset (LPD, right hemisphere dysfunction) were administered measures of verbal (Hopkins Verbal Learning Test-Revised) and visual memory (Brief Visual Memory Test-Revised), that require similar task demands and are associated with left or right hemisphere dominance, respectively. The LPD group demonstrated poorer visual than verbal memory, both within group and in comparison to the RPD group. By contrast, the RPD group showed poorer verbal than visual memory within group. These findings suggest that side of motor symptom onset is associated with asymmetrical memory dysfunction.