HYPERURICEMIA IN HYPERPARATHYROIDISM
HYPERURICEMIA IN HYPERPARATHYROIDISM
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DOI：
10.1056/nejm196107202650302
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发表时间：
1961-01-01
影响因子：
158.5
通讯作者：
CANARY, JJ
中科院分区：
文献类型：
--
作者：
MINTZ, DH;KYLE, LH;CANARY, JJ
8例原发性甲状旁腺功能亢进患者中4例出现高尿酸血症。高尿酸血症组中有2例患者有痛风或痛风家族史，而其他患者无任何解释。手术矫正甲状旁腺功能亢进后，血清尿酸水平仍然升高。引用了具有类似结论的案例。研究表明甲状旁腺功能和尿酸代谢之间没有直接的生理相关性。建议对痛风患者，特别是复发性输尿管结石患者，应进行高甲状旁腺功能检查，对怀疑原发性高甲状旁腺功能的患者应检查高尿酸血症。
Hyperuricemia was found in 4 of 8 patients with primary hyperparathyroidism. Gout or a family history of gout was noted in 2 patients of the hyperuricemic group, whereas no explanation was found in the others. Serum uric levels remained elevated after surgical correction of the hyperparathyroidism. Cases with similar findings are cited. Studies revealed no direct physiologic correlation between parathyroid function and uric acid metabolism. It was suggested that gouty patients, particularly those with recurrent ureterai lithiasis, should be screened for hyperparathyroidism and that hyperuricemia should be sought in suspected cases of primary hyperparathyroidism.