Bacterial transporters for sulfate and organosulfur compounds
Bacterial transporters for sulfate and organosulfur compounds
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DOI：
10.1016/s0923-2508(01)01199-8
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发表时间：
2001-04-01
影响因子：
2.6
通讯作者：
Kertesz, MA
中科院分区：
文献类型：
--
作者：
Kertesz, MA
微生物需要硫来生长，并从无机硫酸盐或有机硫化合物如磺酸盐、硫酸酯或含硫氨基酸中获得硫。硫酸盐转运到细胞中由ATP结合盒（ABC）型转运蛋白（SulT家族）或主要易化超家族型转运蛋白（SulP家族）催化。相比之下，迄今为止鉴定的磺酸盐和硫酸酯转运蛋白都是ABC型系统，其合成受到细胞硫供应的严格调控，由CysB蛋白和LysR家族的其他转录调节因子介导。(C)2001年，Elsevier SAS科学与医学版。
Microorganisms require sulfur for growth, and obtain it either from inorganic sulfate or from organosulfur compounds such as sulfonates, sulfate esters, or sulfur-containing amino acids. Transport of sulfate into the cell is catalyzed either by ATP binding cassette (ABC)-type transporters (SulT family) or by major facilitator superfamily-type transporters (SulP family). By contrast, the sulfonate and sulfate ester transporters identified to date are all ABC-type systems, whose synthesis is tightly regulated by the sulfur supply to the cell, mediated by the CysB protein and other transcriptional regulators of the LysR-family. (C) 2001 Editions scientifiques et medicales Elsevier SAS.