EFFECTS OF HYBRID CYCLE AND HANDCYCLE EXERCISE ON CARDIOVASCULAR DISEASE RISK FACTORS IN PEOPLE WITH SPINAL CORD INJURY: A RANDOMIZED CONTROLLED TRIAL

EFFECTS OF HYBRID CYCLE AND HANDCYCLE EXERCISE ON CARDIOVASCULAR DISEASE RISK FACTORS IN PEOPLE WITH SPINAL CORD INJURY: A RANDOMIZED CONTROLLED TRIAL
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DOI:
10.2340/16501977-1946
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发表时间:
2015-06-01
影响因子:
3.5
通讯作者:
Janssen, Thomas W. J.
Janssen, Thomas W. J.
中科院分区:
医学3区
文献类型:
--
作者:
Bakkum, Arjan J. T.;Paulson, Thomas A. W.;Janssen, Thomas W. J.

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目的:研究16周的运动计划的效果,使用混合循环或手骑自行车,对心血管疾病的危险因素的人与脊髓injure.Participants:19个人与脊髓损伤>= 8 years.Design:多中心随机对照试验。混合自行车组(n = 9)和手动自行车组(n = 10)每周训练两次,共16周。计划前后获得的结果指标为:代谢综合征成分(腰围、收缩压和舒张压、高密度脂蛋白胆固醇、甘油三酯和胰岛素抵抗)、炎症状态(C-反应蛋白(CRP)、白细胞介素(1)-6和-10)与内脏性肥胖结果:对于所有结果测量,两个训练组之间随着时间的推移没有显著差异。腰围(p = 0.001)、舒张压(p = 0.03)、胰岛素抵抗(p = 0.006)、CRP(p = 0.05)、IL-6(p = 0.04)、IL-6/IL-10比值(p = 0.03)、躯干(p = 0.04)和android(p = 0.02)脂肪百分比总体上显著降低。收缩压、甘油三酯、高密度脂蛋白胆固醇、IL-10以及躯干和男性脂肪量均未观察到显著的时间主效应。这项为期16周的运动计划,无论是使用混合自行车还是手动自行车,都发现了对代谢综合征成分、炎症状态和内脏肥胖的类似有益效果,表明功能性电刺激诱导的腿部锻炼与单独的手自行车锻炼相比没有额外的益处。
Objective: To examine the effects of a 16-week exercise programme, using either a hybrid cycle or a handcycle, on cardiovascular disease risk factors in people with spinal cord injury.Participants: Nineteen individuals with spinal cord injury >= 8 years.Design: Multicentre randomized controlled trial. Both the hybrid cycle group (n = 9) and the handcycle group (n = 10) trained twice a week for 16 weeks on the specific cycle. Outcome measures obtained pre and post the programme were: metabolic syndrome components (waist circumference, systolic and diastolic blood pressure, high-density lipoprotein cholesterol, triglycerides and insulin resistance), inflammatory status (C-reactive protein (CRP), interleukin (1)-6 and -10), and visceral adiposity (trunk and android fat).Results: For all outcome measures, there were no significant differences over time between the 2 training groups. Overall significant reductions were found for waist circumference (p = 0.001), diastolic blood pressure (p = 0.03), insulin resistance (p = 0.006), CRP (p = 0.05), IL-6 (p = 0.04), IL-6/IL-10 ratio (p = 0.03), and trunk (p = 0.04) and android (p = 0.02) fat percentage. No significant main effects for time were observed for systolic blood pressure, triglycerides, high-density lipoprotein cholesterol, IL-10, and trunk and android fat mass.Conclusion: The 16-week exercise programme, using either a hybrid cycle or a handcycle, found similar beneficial effects on metabolic syndrome components, inflammatory status and visceral adiposity, indicating that there were no additional benefits of functional electrical stimulation-induced leg exercise over handcycle exercise alone.