Castleman’s disease of the head and neck
Castleman’s disease of the head and neck
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卡斯尔曼头颈病
DOI：
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发表时间：
2006
期刊：
影响因子：
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通讯作者：
Heung
中科院分区：
文献类型：
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作者：
J. Song;M. Jung;J. Woo;S. Chae;S. Hwang;Heung
Castleman病是一种罕见的良性疾病，导致进行性淋巴结肿大。本文报告12例头颈部Castleman病，回顾性分析1993年至2002年间所有病理诊断为Castleman病的病例。在12例患者中，颈部是最常见的受累部位，9例（75%）。III级是最常见的亚部位（5例）。在我们的研究中最常见的体征是无症状的颈部肿块。没有患者有任何需要就医的既往史。术前检查，如细针穿刺和放射学检查，对诊断没有帮助。组织病理学评价是作出明确诊断的唯一途径。本研究的组织病理学亚型为透明血管型。所有病例均行手术切除。最短随访时间为24个月，无复发证据。
Castleman’s disease is an uncommon benign disease that causes progressive lymph node enlargement. We report 12 cases of Castleman’s disease in the head and neck region in a retrospective review of the medical records of all patients with the pathological diagnosis of Castleman’s disease during the period of 1993 through 2002. In the 12 patients, the neck was the most commonly involved site with 9 (75%) cases. Level III was the most common subsite (five cases). The most common sign in our study was an asymptomatic neck mass. No patient had any past histories that required medical attention. Preoperative work up such as fine-needle aspiration and radiographic study was not helpful for diagnostic confirmation. The histopathologic evaluation was the only way to make a definitive diagnosis. The histopathologic subtype of our study was hyaline-vascular type. Excision was curative for all cases. There was no evidence of recurrence with a minimum follow-up duration of 24 months.