The role of optic nerve blood flow in the pathogenesis of glaucoma.
The role of optic nerve blood flow in the pathogenesis of glaucoma.
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DOI：
10.1016/j.ohc.2005.04.001
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发表时间：
2005-09-01
期刊：
影响因子：
--
通讯作者：
Garzozi, Hana J
中科院分区：
文献类型：
--
作者：
Harris, Alon;Rechtman, Ehud;Garzozi, Hana J
关于青光眼损害背后的确切机制，已经出现了许多理论，但这种疾病的复杂性质和人眼内部结构的不可访问性限制了目前的知识。眼压升高是青光眼视神经病变最常见的危险因素；对视神经的缺血性损害也被认为是细胞损伤的可能原因。本综述的目的是探讨视神经头部血流动力学在青光眼发病机制中的可能作用。
Many theories have surfaced regarding the exact mechanisms behind glaucomatous damage, but the complex nature of the disease and the inaccessibility of the internal structures of the human eye have limited current knowledge. Increased intraocular pressure is the risk factor most often associated with glaucomatous optic neuropathy; ischemic insult to the optic nerve has also been suggested as a possible cause of cellular damage. The aim of this review is to cover the possible role of optic nerve head hemodynamics in the pathogenesis of glaucoma.