Paternally derived immune priming for offspring in the red flour beetle, Tribolium castaneum
Paternally derived immune priming for offspring in the red flour beetle, Tribolium castaneum
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DOI：
10.1111/j.1365-2656.2009.01617.x
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发表时间：
2010-03-01
影响因子：
4.8
通讯作者：
Kurtz, Joachim
中科院分区：
文献类型：
--
作者：
Roth, Olivia;Joop, Gerrit;Kurtz, Joachim
P>1。哺乳动物、鱼类和鸟类的寄生雌虫可以通过转移胚胎的特异性抗体来增强后代的免疫防御。同样，社会昆虫母亲转移免疫力，尽管无脊椎动物缺乏抗体。女性跨代免疫启动与父母投资理论相一致，因为母亲比父亲在养育后代方面投入更多。然而，当免疫启动与父母的照顾没有直接联系时，就像昆虫在产卵后放弃卵的情况一样，两性都可能从保护后代中受益。使用红粉甲虫，赤拟谷盗，我们表明，父母暴露于热灭活细菌后，跨代免疫启动发生通过父亲以及母亲。这一新发现挑战了传统观点，即在没有父亲照顾的物种中，雄性只向后代提供基因，并提出了父母之间免疫保护任务分工的可能性。
P>1. Parasitized females in mammals, fish and birds can enhance the immune defence of their offspring by transferring specific antibodies for the embryo. Likewise, social insect mothers transfer immunity despite the fact that invertebrates lack antibodies.2. Female trans-generational immune priming is consistent with parental investment theory, because mothers invest more into rearing their offspring than fathers. However, when immune priming is not directly linked to parental care, as is often the case in insects that abandon their eggs after oviposition, both sexes might benefit from protecting their offspring.3. Using the red flour beetle, Tribolium castaneum, we show that after parental exposure to heat-killed bacteria, trans-generational immune priming occurs through fathers as well as mothers.4. This novel finding challenges the traditional view that males provide only genes to their offspring in species without paternal care, and raises the possibility of a division of tasks with respect to immune protection between parents.