Two new C-glucosyl flavonoids from Ziziphus jujube and their anti-inflammatory activity
Two new C-glucosyl flavonoids from Ziziphus jujube and their anti-inflammatory activity
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枣中两种新的C-葡萄糖基黄酮及其抗炎活性
DOI：
10.1080/10286020.2016.1234458
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发表时间：
2017-01-01
影响因子：
1.7
通讯作者：
Zheng, Yu-Zhong
中科院分区：
文献类型：
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作者：
Fu, Qiang;Ma, Yu;Zheng, Yu-Zhong
从酸枣种子中分离到两个新的c -葡萄糖基类黄酮6- o -阿魏酰基spinosin和6- o -阿魏酰基6-对羟基苯甲酰spinosin，并分离到5个已知化合物。根据化学和光谱证据对它们的结构进行了鉴定。化合物1 ~ 7对COX-1和COX-2酶有中等抑制作用。
Two new C-glucosyl flavonoids 6-O-feruloylspinosin and 6-O-feruloyl-6-p-hydroxybenzoylspinosin, together with five known compounds, were isolated from the seeds of Ziziphus jujube (Rhamnaceae family). Their structures were elucidated on the basis of chemical and spectroscopic evidences. Compounds 1-7 showed moderate inhibitory effects against COX-1 and COX-2 enzymes.