A likelihood-ratio test of monophyly

A likelihood-ratio test of monophyly
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DOI:
10.2307/2413530
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发表时间:
1996-12-01
期刊:
影响因子:
6.5
通讯作者:
Nielsen, R
Nielsen, R
中科院分区:
生物学1区
文献类型:
--
作者:
Huelsenbeck, JP;Hillis, DM;Nielsen, R

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许多系统发育分析是由先天指定的群体的单系性所启发或依赖的。而且,许多系统发生学有用的进化问题并不要求正确估计系统发生学的每一个细节,而是依赖于特定群体的单系性(或缺乏单系性)。我们提出了一个似然比检验,比较在有和没有单系约束的情况下估计的最佳树是否有显着差异。模拟表明,当零假设(特定的指定约束)正确时,检验是保守的。我们应用单一性的似然比检验来研究假定已灭绝的袋狼(袋狼)的亲缘关系问题。具体来说,我们检验了以下两个假设:(1)有袋狼不与dasyurids形成单系类群;(2)有袋狼是澳大利亚哺乳动物辐射的基础成员。采用单一性的似然比检验拒绝了这两个假设。
Many phylogenetic analyses are inspired by or depend upon the monophyly of a group specified a priori. Also, many evolutionary problems for which phylogenies are useful do not require every detail of the phylogeny to be estimated correctly but depend upon the monophyly (or lack thereof) of a particular group. We propose a likelihood-ratio test that compares whether the best trees estimated with and without the constraint of monophyly are significantly different. Simulation suggests that the test is conservative when the null hypothesis (a particular specified constraint) is correct. We applied the likelihood-ratio test of monophyly to the question of the relationship of the presumed-extinct marsupial wolf (Thylacinus). Specifically we examined the null hypotheses that (1) the marsupial wolf does not form a monophyletic group with dasyurids and (2) the marsupial wolf is a basal member of the Australian radiation of mammals. Both hypotheses were rejected using the likelihood-ratio test of monophyly.