A longitudinal study of the association between treatment optimism and sexual risk behavior in young adult gay and bisexual men
A longitudinal study of the association between treatment optimism and sexual risk behavior in young adult gay and bisexual men
复制标题
DOI：
10.1097/01.qai.0000127027.55052.22
复制
发表时间：
2004-12-01
影响因子：
3.6
通讯作者：
Kegeles, SM
中科院分区：
文献类型：
--
作者：
Huebner, DM;Rebchook, GM;Kegeles, SM
为了确定对高效抗逆转录病毒治疗的乐观是否与艾滋病病毒阴性的年轻成年男同性恋者和双性恋者的性行为风险有关，并测试对这种联系的两种替代解释：治疗乐观导致性风险增加，或者治疗乐观是既前性风险的结果。从538名HIV阴性或未经检测的男同性恋者和双性恋者(年龄18-30岁)的样本中获得了有关性危险行为、治疗乐观程度和对艾滋病毒感染的感知易感性的数据，他们不是一夫一妻制的。18个月后收集随访数据。在横断面数据中，治疗乐观与与非主要伴侣发生无保护肛交(UAI)的2个月累积发生率有关；然而，这种影响仅在感觉对艾滋病毒感染高度易感的男性中观察到。纵向分析显示，治疗乐观并不能预测随后的UAI，但UAI确实预测了以后的治疗乐观。治疗乐观与年轻成年男同性恋者和双性恋者的性危险行为有关。然而，这些数据表明，乐观情绪可能产生于性风险，而不是先于性风险。
To determine whether optimism about highly active antiretroviral therapy is associated with sexual risk behavior among young adult HIV-negative gay and bisexual men, and to test 2 alternative explanations for this association: that treatment optimism leads to increased sexual risk or that treatment optimism is the result of previous sexual risk. Data on sexual risk behavior, treatment optimism, and perceived susceptibility to HIV infection were obtained from a sample of 538 HIV-negative or untested gay and bisexual men (ages 18-30) who were not in monogamous relationships. Follow-up data were collected 18 months later. In the cross-sectional data, treatment optimism was associated with the 2-month cumulative incidence of unprotected anal intercourse (UAI) with nonprimary partners; however, this effect was observed only among men who felt highly susceptible to HIV infection. Longitudinal analyses revealed that treatment optimism did not predict subsequent UAI, but UAI did predict later treatment optimism. Treatment optimism is associated with sexual risk behavior among young adult gay and bisexual men. However, these data suggest that optimism may result from, rather than precede, sexual risk.