The auditory cortex network in the posterior superior temporal area
The auditory cortex network in the posterior superior temporal area
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DOI：
10.1016/j.clinph.2018.07.014
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发表时间：
2018-10
影响因子：
4.7
通讯作者：
Yuto Suzuki;R. Enatsu;A. Kanno;S. Ochi;N. Mikuni
中科院分区：
文献类型：
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作者：
Yuto Suzuki;R. Enatsu;A. Kanno;S. Ochi;N. Mikuni
本研究采用皮层电刺激结合弥散张量成像（diffusion tensor imaging，DTI）技术，对7例顽固性局灶性癫痫患者（左侧4例，右侧3例）的后外侧上级颞区（posterior lateral superior temporal area，PLST）听觉皮层的功能和网络进行了研究。将50 Hz的电刺激施加到长期植入的硬膜下电极以识别PLST听觉皮层。DTI被用来确定皮质下纤维起源于PLST听觉皮层发现由electricstimulation.ResultsThe右侧PLST听觉皮层电刺激引起的听力障碍的3例患者和左侧刺激引起的听觉错觉的声音在4例患者。DTI检测到所有患者的中纵束（MLF）、6例患者的上级纵束（SLF）和3例患者的额枕下束（IFOF），均起源于PLST听皮层。SLF和IFOF可能与听觉加工有关。
ObjectiveThis study investigated the function and networks of the auditory cortices in the posterior lateral superior temporal area (PLST) using a combination of electrical cortical stimulation and diffusion tensor imaging (DTI).MethodsSeven patients with intractable focal epilepsy in which the PLST auditory cortices were identified during the electrical cortical stimulation were enrolled in this study (left side: four patients, right side: three patients). Electrical stimulation at 50 Hz was applied to the chronically implanted subdural electrodes to identify the PLST auditory cortices. DTI was used to identify the subcortical fibers originating from the PLST auditory cortices found by electrical stimulation.ResultsElectrical stimulation of the right PLST auditory cortices induced hearing impairment in three patients and left side stimulation elicited hearing illusory sounds in four patients. DTI detected the middle longitudinal fasciculus (MLF) in all patients, the superior longitudinal fasciculus (SLF) in six patients and the inferior fronto-occipital fasciculus (IFOF) in three patients, originating from the PLST auditory cortices.ConclusionThis study suggests different functional roles between the right and left PLST auditory cortices, and the networks originating from these areas.SignificanceMLF, SLF and IFOF might be associated with the auditory processing.