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DOI：
10.1046/j.1365-2044.2003.03561.x
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发表时间：
2003-12
期刊：
影响因子：
10.7
通讯作者：
中科院分区：
文献类型：
--
作者：
自从神经外科作为一门专业出现以来，神经麻醉已经发生了不可思议的变化（图1）。虽然在过去十年中发生的变化没有那么引人注目，但这一时期在手术室、放射室和神经危重症护理环境中，麻醉技术仍在稳步发展。其中许多变化源于我们对大脑生理学和病理生理学基础科学的更深入理解，以及新型麻醉剂的开发。另一些则反映了神经外科实践中不断加速的变化步伐。不可避免地，我个人对近期事态发展的看法会带有一定程度的狭隘，对此我深表歉意。然而，我希望下面的描述将在很大程度上反映整个英国神经麻醉实践中的变化。神经外科麻醉的最终目的是提供最佳的颅内手术条件，同时保持适当的脑灌注压和脑氧合。我们的麻醉技术和使用的药理学制剂都是为了满足这些野心。
Neuroanaesthesia has changed beyond all recognition since the advent of neurosurgery as a specialty (Fig. 1). Whilst the changes that have occurred in the last decade have been less dramatic, the period has nonetheless seen a steady evolution of anaesthetic techniques in the operating theatre, radiology suite and the neurocritical care setting. Many of these changes stem from our greater understanding of the science underlying cerebral physiology and pathophysiology and from the development of new anaesthetic agents. Others reflect the ever-accelerating pace of change in neurosurgical practice. Inevitably, a degree of parochialism will creep into this personal view of recent developments and for this I apologise. However, I hope the following description will largely reflect the changes in practice that have occurred in neuroanaesthesia throughout the United Kingdom.Conduct of anaesthesia The ultimate aim of anaesthesia for neurosurgery is to provide optimal intracranial operating conditions whilst maintaining an appropriate cerebral perfusion pressure and cerebral oxygenation. Our anaesthetic techniques and the pharmacological agents used are all directed towards satisfying these ambitions.