Controversy: antenatal steroids.
Controversy: antenatal steroids.
复制标题
争议：产前类固醇。
DOI：
10.1016/j.clp.2011.06.013
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发表时间：
2011
影响因子：
2.1
通讯作者：
Jobe,AlanH
中科院分区：
文献类型：
--
作者：
Wapner,Ronald;Jobe,AlanH
There is no controversy about the core conclusion that women at risk of preterm delivery prior to 32–34 wks gestational age should be treated with antenatal steroids. This practice is supported by the initial comprehensive meta-analysis of Crowley, Chambers, and Keirse in 1990 [1], the NIH Consensus Development Conference in 1994 [2], the second Consensus Conference to evaluate repeated courses of antenatal steroids in 2000 [3], and the practice recommendations of obstetric societies worldwide. Three recent meta-analyses by the Cochrane Collaboration on the benefits of antenatal steroids [4], the choice of steroid and dosing [5], and repeat doses of corticosteroids [6] comprehensively summarize the available clinical information to about 2007. However, there are many unanswered questions about which steroid and dose to use and about their use in selected populations. This review will focus on those areas of uncertainty.
